| Japanese |
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| Title | 99mTc-DMSAの相対的および絶対的腎摂取率に関する検討 : 経時的変化と99mTc-DTPA腎摂取率との相関について |
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| Subtitle | 原著 |
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| Authors | 伊藤和夫*, 浅野嘉文**, 加藤千恵次*, 塚本江利子*, 中駄邦博*, 永尾一彦*, 後藤敏明**, 野々村克也**, 古舘正従* |
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| Authors(kana) | |
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| Organization | *北海道大学医学部核医学教室, **泌尿器科教室 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 3 |
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| Page | 237-242 |
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| Year/Month | 1990/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 99mTc-DMSA腎摂取率の経時的変化, および99mTc-DTPAの摂取率 (2-3分) との相関について検討を行った. 放射能の時間減衰および組織吸収補正を行った99mTc-DMSAの絶対的 (総腎) 腎摂取率は, 心不全の1例を除き5時間まで経時的に増強した. 一方, バックグラウンド補正のみから算出した腎の正味集積カウント数は, 2-3時間でピークが観察された. 99mTc-DMSA腎摂取率 (2時間値) と99mTc-DTPA腎摂取率 (2-3分) 値との比較では, 相対的分腎摂取率には有意な相関 (r=0.992, p<0.001) が得られたが, 腎機能の指標となる絶対的両腎摂取率には有意な相関 (r=0.419) は得られなかった. 99mTc-DMSAの相対的分腎摂取率は, 99mTc-DTPAとの相関が高く, 定量的腎機能情報となりうる. しかし, 絶対的腎摂取率に関しては両者の相関が低く, その臨床的評価に関しては, 99mTc-DMSAの経時的変化を考慮した正常値の設定が必要である. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-DMSA, Renal uptake, 99mTc-DTPA, Gamma camera |
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| English |
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| Title | Quantitation of Absolute and Relative Renal Uptake Using 99mTc-DMSA : Sequential Change in Time and Correlation to 99mTc-DTPA Uptake |
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| Subtitle | Original Articles |
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| Authors | Kazuo ITOH*, Yoshihumi ASANO**, Chietsugu KATO*, Kunihiro NAKADA*, Kazuhiko NAGAO*, Toshiaki GOTO**, Katsuta NONOMURA**, Masayori FURUDATE* |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine, Hokkaido University School of Medicine, **Department of Urology, Hokkaido University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 3 |
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| Page | 237-242 |
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| Year/Month | 1990/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A renal uptake of 99mTc-DMSA as a function of time and correlation between 99mTc-DMSA and 99mTc-DTPA in renal uptake were discussed. The absolute renal uptake of 99mTc-DMSA calculated by complete correction of tissue attenuation and physical decay showed increase by 5 hours after the administration, except one case with congestive heart failure. The net renal counts attained a maximum between 2 to 3 hours after the administration. There was a good correlation (r=0.992, p<0.001) between the relative renal uptake of 99mTc-DMSA (2hour) and that of 99mTc-DTPA (2-3min). On the contrary, the absolute renal uptake of 99mTc-DMSA as a indicator of total renal function showed a poor correlation (r=0.419) to GFR calculated from 99mTc-DTPA. The results indicate that the relative renal uptake of 99mTc-DMSA is a reliable quantitative parameter for split renal function. However, the absolute renal uptake of 99mTc-DMSA may be suggested to be a different renal functioning indicator from GFR calculated from 99mTc-DTPA. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-DMSA, Renal uptake, 99mTc-DTPA, Gamma camera |
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