Japanese
Title冠動脈血行再建術前後における, 局所心筋血流量およびフルオロデオキシグルコース集積の定量的検討
Subtitle原著
Authors高橋晶*, 飯田秀博**, 菅野巖**, 小野幸彦*, 宍戸文男**, 犬上篤**, 村上松太郎**, 上村和夫**, 佐藤匡也***, 阿部芳久***, 門脇謙***, 熊谷正之***
Authors(kana)
Organization*秋田県立脳血管研究センター内科, **放射線科, ***成人病医療センター循環器科
Journal核医学
Volume27
Number3
Page227-235
Year/Month1990/3
Article原著
Publisher日本核医学会
Abstract「要旨」 冠動脈血行再建術を施行した虚血性心疾患患者5例に, O-15標識水およびF-18標識フルオロデオキシグルコースのダイナミックPETを術前と術後に施行し, 局所心筋血流量 (MBF) , および空腹時心筋FDG集積 (MFU) を定量的に検討した. 血行再建術後の冠動脈造影で開存のあった領域では, MBFが術前の0.59±0.17ml/min/gから術後0.77±0.14ml/min/gと増加 (p<0.05) , さらに開存ありの領域に無関係に評価した場合も, MBFは術前の0.69±0.22ml/min/gから術後0.83±0.18ml/min/gと有意に増加した (p<0.05) . 空腹時MFUは, 開存のありの領域とは無関係に, 術前の値が高値な部位ほど術後に低下した (p<0.005) . 冠動脈血行再建術の効果の目安となる術前後のMFUの有意な低下は, 術前MFUが約0.03以上でみられた.
Practice臨床医学:一般
KeywordsMyocardial blood flow, Fluoro-deoxyglucose, Aorto-coronary bypass operation, Ischemic heart disease, Dynamic positron emission tomography
English
TitleQuantitative Evaluation of Myocardial Blood Flow and Myocardial Fluoro-deoxyglucose Uptake Determined by PET before and after Aorto-coronary Bypass Operation in Patients with Ischemic Heart Disease
SubtitleOriginal Articles
AuthorsAkira TAKAHASHI*, Hidehiro IIDA**, Iwao KANNO**, Yukihiko ONO*, Kazuo UEMURA**, Fumio SHISHIDO**, Atsushi INUGAMI**, Matsutaro MURAKAMI**, Tadaya SATO***, Yoshihisa ABE***, Ken KADOWAKI***, Tadayuki KUMAGAI***
Authors(kana)
Organization*Division of Internal Medicine, **Division of Radiology, Research Institute of Brain and Blood Vessels-AKITA, ***Akita Medical Center
JournalThe Japanese Journal of nuclear medicine
Volume27
Number3
Page227-235
Year/Month1990/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Absolute myocardial blood flow (MBF) and myocardial FDG uptake (MFU) in the fasting state were determined in 5 patients who underwent aorto-coronary bypass operation, using O-15 water, F-18 fluoro-deoxyglucose and dynamic PET before and after the operation. In the patent graft region, MBF was increased from 0.59+-0.17 ml/min/g to 0.77+-0.14 ml/min/g (p<0.05) . Mean MBF was increased from 0.69+-0.22 ml/min/g to 0.83+-0.18 ml/min/g (p<0.05) . MFU in the fasting state was significantly decreased in high MFU region compared with low MFU region (p<0.005) . Quantitative evaluation of MBF and MFU before aorto-coronary bypass operation was quite useful to determine adequate indication of the operation.
PracticeClinical medicine
KeywordsMyocardial blood flow, Fluoro-deoxyglucose, Aorto-coronary bypass operation, Ischemic heart disease, Dynamic positron emission tomography

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