| Japanese |
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| Title | 死腔を介した81mKr持続吸入法の臨床評価 |
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| Subtitle | 原著 |
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| Authors | 黒澤弘美*, 松林さつき*, 石井裕子*, 石田博英**, 平沢之則**, 森豊**, 川上憲司**, 島田孝夫*** |
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| Organization | *東京慈恵会医科大学中央検査部, **放射線科, ***第三内科 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 2 |
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| Page | 125-131 |
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| Year/Month | 1990/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 通常の81mKrガス持続吸入法 (VE) に死腔を介しての持続吸入法 (VL) を加え, 両者の放射能分布の組み合わせを利用して, 種々呼吸器疾患の病態について検討した. 110名の各種肺疾患を対象として81mKr持続吸入検査を行った. 検査は座位で行い, 81mKr吸入分布は, 背面より指向したシンチカメラで撮像した. VEとVLのイメージの組み合わせにより4つのグループに分類された. グループ1は, VE, VLの両者に異常がなく正常とした. グループ2はVLに比してVEの欠損が大きかった症例群, グループ3は, VEがVLに比して欠損の大きかった例, グループ4はVEとVLが同程度の異常を示したグループである. グループ2には喘息寛解期の症例が多く含まれていた. グループ3は2つのサブグループに分類されたが, グループ3・2には肺線維症の割合が多かった. グループ4には高度の閉塞性肺疾患や肺線維症が含まれていた. 通常の81mKr持続吸入法に死腔を加えた吸入法を加味することにより, 呼吸器病変の病態をより詳細に検討し得た. |
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| Practice | 臨床医学：一般 |
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| Keywords | Kr-81m inhalation study, Dead space, Chronic obstructive pulmonary disease, pulmonary fibrosis |
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| English |
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| Title | Clinical Evaluation of Kr-81m Inhalation Study through a Dead Space |
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| Subtitle | Original Articles |
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| Authors | Hiromi KUROSAWA*, Satsuki MATSUBAYASHI*, Yasuko ISHII*, Hirohide ISHIDA**, Yukinori HIRASAWA**, Yutaka MORI**, Takao SHIMADA***, Kenji KAWAKAMI** |
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| Authors(kana) | |
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| Organization | *Department of Clinical Laboratory, **Department of Radiology, ***The Third Department of Medicine, Jikei University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 2 |
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| Page | 125-131 |
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| Year/Month | 1990/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A new inhalation technique of 81mKr gas was applied to evaluate the pathophysiological abnormality of ventilation. 81mKr gas (370 MBq) was continuously supplied into a mouth piece directly (without dead space) , VE, or through a dead space of 500m/l, VL, in 110 subjects with various lung diseases. Subjects were divided in four groups by a combination of distribution patterns of 81mKr gas obtained by these two inhalation techniques. [Group 1] : No ventilatory defect in both techniques. [Group 2] : Defects larger in VE than VL. [Group 3] : Defects larger in VL than VE. [Group 4] : No remarkable difference in defects in both techniques. Cases of group 1 were normal in pulmonary function test and chest X-ray. Finding of group 2 reflects early airway closure. This group consisted of cases in remission of bronchial asthma, small air way disease and pulmonary congestion. In group 3, restrictive disease and obstructive disease, especially emphysema, were included. Patients with severe obstructive disease and organized change of pulmonary parenchyma were belonged in group 4. In ventilation study with 81mKr gas, a combined study of inhalation technique through a dead space and by direct infusion may be useful to evaluate a pathophysiological change of various pulmonary diseases. |
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| Practice | Clinical medicine |
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| Keywords | Kr-81m inhalation study, Dead space, Chronic obstructive pulmonary disease, pulmonary fibrosis |
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