| Japanese |
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| Title | 運動負荷201Tl心筋シンチグラフィにおける安静時少量追加投与の試み (第1報) - 24時間像および局所壁運動との対比検討 - |
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| Subtitle | 原著 |
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| Authors | 大谷弘*, 玉木長良*, 米倉義晴*, 野原隆司**, Ishtiaque H. MOHIUDDIN*, 小野晋司**, 神原啓文**, 河合忠一**, 平田和男***, 伴敏彦***, 小西淳二* |
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| Authors(kana) | |
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| Organization | *京都大学医学部放射線核医学科, **第三内科, ***心臓血管外科 |
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| Journal | 核医学 |
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| Volume | 27 |
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| Number | 1 |
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| Page | 9-15 |
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| Year/Month | 1990/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 虚血性心疾患37例に, 運動負荷201Tl心筋SPECTの3時間像撮像後に安静時201Tl少量追加投与を試み, その有用性を検討した. 3時間像で固定性欠損であった52区域の中で19区域 (37%) は, 少量追加投与により再分布がみられた. 3時間像で不完全再分布であった43区域の中で, 15区域 (35%) は少量追加投与により完全再分布となった. また24時間遅延像も9例に施行したが, 3時間像で固定性欠損であった13区域の中の5区域 (38%) で再分布が明らかになったが, 逆に3時間像で再分布のみられた7区域の中の3区域 (43%) で再分布がみられなくなった. なお, 3時間像では固定性欠損, 少量追加投与により再分布が明らかになった区域の壁運動異常 (壁運動スコア=1.65±1.17) は, 固定性欠損のままであった区域 (2.29±1.05) より軽度であった (p<0.05) . 以上より, 運動負荷201Tl心筋SPECTに少量追加投与法を併用することにより再分布の判定が向上し, かつ少量追加投与で生じた再分布のある領域は, 壁運動が保たれる傾向にあった. 24時間像と比べて画質が良いことと, 当日のうちに検査ができるという利点もあり, 少量追加投与法は心筋viabilityの評価に有用と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Coronary artery disease, Tl-201, Viability, 24-hour scan, Regional wall motion |
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| English |
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| Title | Assessment of Resting Thallium-201 Reinjection after Stress-Delayed Tl Imaging (I) : Comparison with 24-hour Scan and Regional Wall Motion |
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| Subtitle | Original Articles |
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| Authors | Hiroshi OHTANI*, Nagara TAMAKI*, Yoshiharu YONEKURA*, Ryuji NOHARA**, Ishtiaque H. MOHIUDDIN*, Shinji ONO**, Hirofumi KAMBARA**, Chuichi KAWAI**, Kazuo HIRATA***, Toshihiko BAN***, Junji KONlSHI* |
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| Authors(kana) | |
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| Organization | *Department of Radiology and Nuclear Medicine, **Third Division, Department of Internal Medicine, ***Department of Cardiovascular Surgery, Kyoto University Faculty of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 27 |
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| Number | 1 |
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| Page | 9-15 |
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| Year/Month | 1990/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Clinical value of resting reinjection of 1 mCi (37MBq) of T1 after stress-delayed scan was assessed in comparison with 24 hr delayed scan and regional wall motion (RWM) in 37 patients with coronary artery disease. Of 101 segments with initial perfusion abnormality, concordant findings were observed after T1 reinjection in 67 segments (66%) . But redistribution (RD) after T1 reinjection was observed in 19 of the 52 persistent defect (PD) segments (37%) , and complete RD was observed 15 of the 43 segments (35%) where 3 hr scan showed incomplete RD. On the other hand, concordant findings were observed on 24 hr delayed scan in 11 of the 20 segments with perfusion abnormality (55%) . RD on 24 hr delayed scan was observed in 5 of the 13 PD (38%) , but it was not apparent in 3 of the 7 segments where 3 hr scan showed RD. Furthermore the segments which showed RD after T1 reinjection in PD segments tend to have less severe RWM abnormality than the sustained PD segments (RWM score : 1.65+-1.17 vs. 2.29+-1.05, P<0.05) . These data indicate that T1 reinjection which permits assessment of RD with good quality images on the same day is considered as a valuable means for assessing myocardial viability. |
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| Practice | Clinical medicine |
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| Keywords | Coronary artery disease, Tl-201, Viability, 24-hour scan, Regional wall motion |
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