| Japanese |
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| Title | 運動負荷201Tl心筋SPECTの定量解析法による心筋viabilityの再評価 - FDG-PETとの対比検討 - |
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| Subtitle | 原著 |
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| Authors | 大谷弘*, 玉木長良*, 山下敬司*, 米倉義晴*, 間賀田泰寛*, 佐治英郎*, Ishtiaque H. MOHIUDDIN*, 野原隆司**, 神原啓文**, 河合忠一**, 平田和男***, 伴敏彦***, 小西淳二* |
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| Authors(kana) | |
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| Organization | *京都大学医学部放射線核医学科, **第三内科, ***心臓血管外科 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 11 |
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| Page | 1389-1398 |
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| Year/Month | 1989/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 虚血性心疾患30例に運動負荷201Tl心筋SPECTとポジトロンCTを施行し, その検査所見を対比して201Tl心筋SPECTによる心筋viabilityの判定について検討した. 201Tl心筋SPECT像で血流の低下を示した104区域において, 視覚法で固定性欠損と判定された74区域の中で, Bull's eye同心円表示法により31区域 (42%) に再分布 (微少再分布) を認めた. これらはすべて18FDGの所見よりviableな心筋であった. すなわち, 視覚法では同定しきれなかったviableな心筋の49区域の中で, この定量解析法により, 31区域 (63%) がviableな心筋と正しく同定された. しかしながら, 定量解析法を用いても固定性欠損と判定された区域の中で, 18区域 (42%) は18FDGの所見よりviableな心筋と判定され, 血流情報と代謝情報の相違は残った. 以上より, 201Tl心筋SPECT像より心筋のviabilityを評価するためには, 定量解析を含めた再分布の有無を検討することが有用であることが示唆された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Position emission tomography, Tl-201, Viability, Redistribution, 18F-fluorodeoxyglcose |
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| English |
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| Title | Assessment of Myocardial viability by Quantitative Analysis of stress Tl-SPECT - Comparison with FDG-PET - |
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| Subtitle | Original Articles |
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| Authors | Hiroshi OHTANI*, Nagara TAMAKI*, Keiji YAMASHITA*, Yoshiharu YONEKURA*, Yasuhiro MAGATA*, Hideo SAJI*, Ishtiaque H.MOHIUDDIN*, Ryuji NOHARA**, Hirofumi KAMBARA**, Chuichi KAWAI**, Kazuo HIRATA***, Toshihiko BAN***, Junji KONISHI* |
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| Authors(kana) | |
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| Organization | *Department of Radiology and Nuclear Medicine, **Third Division, Department of Internal Medicine, ***Department of Cardiovascular Surgery, Kyoto University Faculty of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 11 |
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| Page | 1389-1398 |
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| Year/Month | 1989/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Stress Tl-201 tomography (SPECT) is widely used for evaluating myocardial viability. To assess its value, redistribution (RD) on SPECT was compared with metabolic imaging using FDG. Thirty patients with coronary artery disease underwent stress-3 hour Tl-201 SPECT and PET using N-13 ammonia and FDG. RD was classified into 4 grading, including complete RD (CR) , incomplete RD (IR) , persistent defect (PD) and additional minimal RD (MR) defined as no definite RD on visual analysis but faint RD with Bull's eye quantitative analysis (QNT) . All but one segment with CR or IR were viable regions (normal or ischemic regions) by PET. Of 74 segments without RD on visual analysis, 31 segments (42%) had RD by QNT (MR) . All of them were viable regions by PET. Thus, QNT identified 31 segments (63%) of the metabolically viable segments which the visual Tl-201 analysis did not show RD and classified as myocardial scar. However, even such QNT cannot detect ischemic myocardium in 18 segments (42%) containing metabolic activity on PET. These data indicate that QNT of RD on Tl-201 SPECT is considered as a valuable means for assessing myocardial ischemia. |
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| Practice | Clinical medicine |
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| Keywords | Position emission tomography, Tl-201, Viability, Redistribution, 18F-fluorodeoxyglcose |
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