| Japanese |
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| Title | 急性および慢性炎症性疾患における111In標識白血球シンチグラフィと67Gaシンチグラフィの臨床的比較検討 |
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| Subtitle | 原著 |
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| Authors | 齋藤知保子*, 伊藤和夫** |
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| Organization | *市立札幌病院放射線科, **北海道大学医学部核医学教室 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 10 |
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| Page | 1303-1310 |
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| Year/Month | 1989/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 急性および慢性炎症性疾患, あるいは分離白血球の集積が期待された56症例に59回の111In標識白血球シンチグラフィ (ILLS) と67Gaシンチグラフィ (67Ga) をほぼ同時期に施行し, 両者の病巣検出能, シンチグラム所見の差異と臨床経過との関連について検討した. 検討対象とした全80部位におけるILLSの感染巣に対するsensitivityは60.5%, 67Gaでは94.7%であり, specificityは前者は78.6%, 後者では47.6%であった. 化膿巣に対するsensitivityは, ILLSでは95.5%, 67Gaでは90.9%を示した. ILLSで感染巣が陽性所見として描出されるには症状発現から遅くとも約3週以内に検査する必要があった (P<0.005) . また検査時におけるC-reactive protein levelは, ILLS陽性所見と一致する結果が得られた (P<0.05) . ILLSでは, 比較的病巣の中心部に明瞭な集積を示すのに対して, 67Gaでは病巣辺縁にドーナツ状の集積を示す傾向がみられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 111In labeled luekocyte scintigraphy, 67Ga scintigraphy, Infection |
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| English |
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| Title | The Clinical Comparison between 111In Labeled Leukocyte and 67Ga Scintigraphy in Acute and Chronic Inflammatory Diseases |
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| Subtitle | Original Articles |
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| Authors | Chihoko SAITOH*, Kazuo ITOH** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Sapporo General Hospital, **Department of Nuclear Medicine, Hokkaido University, School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 10 |
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| Page | 1303-1310 |
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| Year/Month | 1989/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 111In labeled leukocyte scintigraphy (ILLS) and 67Ga sintigraphy (67Ga) were carried out in 56 patients (59 studies) with clinical suspicion of acute or chronic inflammation. The diagnosis of inflammation was based on cultures, autopsy findings, radiographic studies, and clinical course. The overall sensitivity and specificity to infectious foci for ILLS, considering all 80 sites studied, were 60.5%, 78.6%, and those for 67Ga were 94.7%, 47.6%. As to suppurative foci, sensitivity of ILLS and 67Ga were 95.5% and 90.9%. The duration from the onset of clinical symptoms to examination in patients with positive ILLS were significantly (p<0.005) shorter than in patients with negative ILLS. Also the C-reactive protein levels in patients with positive ILLS were significantly (p<0.05) higher than in patients with negative ILLS. Different accumulation patterns between ILLS and 67Ga were shown in 17 foci out of 21 lesions. ILLS tended to accumulate to the center of lesions strongly. On the other hand, 67Ga tended to concentrate peripherally like doughnut pattern. |
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| Practice | Clinical medicine |
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| Keywords | 111In labeled luekocyte scintigraphy, 67Ga scintigraphy, Infection |
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