| Japanese |
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| Title | SPECTによる肺の画像再構成と肺組織容積の算定に関する基礎的検討 |
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| Subtitle | 原著 |
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| Authors | 金沢実*, 鈴木幸男*, 藤島清太郎*, 横山哲朗*, 尾川浩一**, 久保敦司**, 橋本省三** |
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| Organization | *慶應義塾大学医学部内科学教室, **放射線科学教室 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 10 |
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| Page | 1285-1293 |
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| Year/Month | 1989/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 SPECT (single photon emission computed tomography) を呼吸器疾患の画像診断や呼吸機能評価に応用するための基礎的検討として, 肺再構成画像の画質を評価し肺組織容積を算出した. 肺ファントムを用いた実験によりSPECT画像と臓器容積を推定する際の画像再構成条件を検討した. 臨床例に関しては6名の健常対象において肺気量を変化させて, 肺SPECT画像の変化を描出することができた. また肺組織容積を算出したところ機能的残気量と相関 (r=0.91) を示した. SPECTは呼吸器疾患における肺気量や肺血管床などの変化を視覚化するとともに定量評価し得る点で有用であることが示唆された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Single photon emission computed tomography (SPECT) , Lung tissue volume, Continuous negative pressure, Positive end-expiratory pressure, Radionuclide lung imaging |
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| English |
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| Title | Exploration on the Reconstruction of Lung Image and the Estimation of Lung Tissue Volume by Single Photon Emission Computed Tomography (SPECT) |
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| Subtitle | Original Articles |
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| Authors | Minoru KANAZAWA*, Yukio SUZUKI*, Seitaro FUJISHIMA*, Tetsuro YOKOYAMA*, Koichi OGAWA**, Atsushi KUBO**, Shozo HASHIMOTO** |
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| Authors(kana) | |
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| Organization | *Department of Medicine, **Department of Radiology, School of Medicine, Keio University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 10 |
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| Page | 1285-1293 |
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| Year/Month | 1989/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] We studied the use of single photon emission computed tomography (SPECT) for evaluating lung image and measuring lung tissue volume, in a lung phantom and healthy volunteers. Three conditions of image processing were tested using the phantom, and found out a backprojection method with using a Shepp-Logan filter and a pre-reconstruction smoothing of 3×3 pixels to be suited. A lung tissue volume was estimated from the summation of voxels in the region where the SPECT value was greater than an arbitrary threshold level. We changed phantom lung density from 0.34 g/cm3 to 0.58 g/cm3, but there was no significant effect in the estimated volume by the density change. Changes in the lung SPECT images and lung tissue volumes in healthy subjects were studied, after changing the lung volume by applying either continuous negative bodysurface pressure (CNP) to the thorax or positive end-expiratory pressure (PEEP) . Difference of the lung expansion in the two methods was visualized by the SPECT images. The lung tissue volumes obtained by SPECT were correlated with the functional residual capacity by Helium dilution method (r=0.91, p<0.001). We concluded that lung SPECT could be used clinically to display the distribution of a tracer radio-isotope in the lungs and also used to estimate the lung tissue volume. |
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| Practice | Clinical medicine |
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| Keywords | Single photon emission computed tomography (SPECT) , Lung tissue volume, Continuous negative pressure, Positive end-expiratory pressure, Radionuclide lung imaging |
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