| Japanese |
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| Title | 133Xeを用いた経直腸門脈シンチグラフィによる肝血流量の測定 |
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| Subtitle | 原著 |
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| Authors | 塩見進*, 黒木哲夫*, 植田正*, 小林絢三*, 池岡直子**, 門奈丈之**, 越智宏暢***, 小野山靖人*** |
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| Organization | *大阪市立大学医学部第三内科, **公衆衛生, ***放射線科 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 10 |
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| Page | 1279-1284 |
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| Year/Month | 1989/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 133Xeを用いた経直腸門脈シンチグラフィを行い, そのtime-activity curveを解析することにより肝血流量の測定を試みた. 肝および門脈でのtime-activity curveより肝における減衰曲線を作成し, height over area法にて肝血流量を算出した. 肝血流量は慢性非活動性肝炎143±17.1ml/100g/min, 慢性活動性肝炎119±20.2ml/100g/min, 肝硬変73.2±23.4ml/100g/minであり肝硬変において有意の低下を認めた. また, 肝右葉・左葉血流比は慢性肝炎では全例1以上であったが, 肝硬変では1以下の例も存在し, 両者の組み合わせにより肝硬変の鑑別が可能と思われた. この方法は侵襲的操作が必要でなく, 生理的状態での肝血流量が測定できることより, 臨床的に応用可能と思われた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Per-rectal portal scintigraphy, Hepatic blood flow, 133Xe, Liver cirrhosis, Chronic hepatitis |
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| English |
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| Title | Measurement of Regional Hepatic Blood Flow with 133Xe Per-rectal Portal Scintigraphy |
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| Subtitle | Original Articles |
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| Authors | Susumu SHIOMI*, Tetsuo KUROKI*, Tadashi UEDA*, Kenzo KOBAYASHI*, Naoko IKEOKA**, Takeyuki MONNA**, Hironobu OCHI***, Yasuto ONOYAMA*** |
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| Authors(kana) | |
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| Organization | *Third Department of Internal Medicine, **Department of Public Health, ***Department of Radiology, Osaka City University Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 10 |
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| Page | 1279-1284 |
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| Year/Month | 1989/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The hepatic blood flow (HBF) of patients with liver disease was measured by per-rectal portal scintigraphy with the use of 133Xe. To analyze the time-activity curves of the liver and portal vein, washout curves of the liver were plotted, and from those, the HBF and the ratio of the HBF of the right lobe of the liver to that of the left lobe (R/L ratio) were calculated. The HBF were 143+-17 ml/100 g/min in 5 patients with chronic inactive hepatitis, 119+-20 ml/100 g/min in 4 patients with chronic active hepatitis, and 73.2+-23.4 ml/100 g/min in 7 patients with cirrhosis of the liver. All of four patients whose HBF was under 100 ml/100 g/min and whose R/L ratio was under 1.0 had cirrhosis of the liver. Only one of the 9 patients whose HBF was over 100 ml/100 g/min and whose R/L ratio was over 1.0 had cirrhosis of the liver. The results suggested that per-rectal portal scintigraphy is a useful and noninvasive method to measure the hepatic blood flow. |
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| Practice | Clinical medicine |
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| Keywords | Per-rectal portal scintigraphy, Hepatic blood flow, 133Xe, Liver cirrhosis, Chronic hepatitis |
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