| Japanese |
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| Title | 運動負荷first-pass radionuclide ventriculographyによる虚血性心疾患の診断 - sector法を用いて - |
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| Subtitle | 原著 |
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| Authors | 竹石恭知*, 殿岡一郎*, 目黒光彦*, 星光*, 山口佳子*, 政金生人*, 立木楷*, 安井昭二*, 駒谷昭夫**, 高橋和栄*** |
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| Authors(kana) | |
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| Organization | *山形大学医学部第一内科, **放射線科, ***附属病院放射線部 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 9 |
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| Page | 1169-1176 |
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| Year/Month | 1989/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 運動負荷first-pass radionuclide ventriculographyを冠動脈疾患患者65例, 正常冠動脈を有する18例に施行した. 左室を5つのsectorに分割し, 左室全体と各sectorごとに容量曲線を作製し, LVEF, Time to End Systole (TES) を算出した. 各sectorについて, そのTESと左室全体のTESの差をそれぞれ求め, その平均値をVariation of TESとし, 左室asynchronyの指標とした. LVEFでは正常冠動脈症例のmean-2SD値以下を, Variation of TESではmean+2SD値以上を異常とし, 冠動脈疾患の検出を行った. 全83例におけるsensitivity, specificityはそれぞれ, LVEFでは安静時35%, 83%, 運動負荷時63%, 83%, 負荷による変化分 (Δ) 51%, 83%, Variation of TESでは安静時75%, 78%, 運動負荷時88%, 83%, Δ60%, 89%であった. 心筋梗塞を認めないNo MI群33例におけるsensitivityは, LVEFでは安静時9%, 運動負荷時52%, Δ58%であり, Variation of TESでは安静時64%, 運動負荷時94%, Δ73%であった. 運動負荷時のVariation of TESは運動負荷時LVEF, ΔLVEFよりも有意に高い診断率を示した (p<0.01) . また1枝病変例のLVEFによる診断率は, 運動負荷時, Δとも31%と低かったが, Variation of TESでは, 運動負荷時100%, Δ62%であり, LVEFに比し高かった. このようにVariation of TESは, 心筋虚血により惹起される左室asynchronyを鋭敏に反映し, 冠動脈疾患の検出に有用な指標であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | First-pass radionuclide ventriculography, Coronary artery disease, Sector analysis |
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| English |
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| Title | Detection of Coronary Artery Disease by Exercise Radionuclide Ventriculography : Using Sector Analysis |
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| Subtitle | Original Articles |
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| Authors | Yasuchika TAKEISHI*, Ichiro TONOOKA*, Mitsuhiko MEGURO*, Hikaru HOSHI*, Yoshiko YAMAGUCHI*, Ikuto MASAKANE*, Kai TSUIKI*, Shoji YASUI*, Akio KOMATANI*, Kazuei TAKAHASHI*** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medieine, **Department of Radiology, Yamagata University School of medicine, ***Department of Radiology, Yamagata University Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 9 |
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| Page | 1169-1176 |
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| Year/Month | 1989/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Exercise first-pass radionuclide ventriculography was performed on 65 patients with coronary artery disease (CAD) and 18 control subjects with normal coronary artery. Left ventricle (LV) was divided into 5 sectors in radial, and volume curves were generated for whole LV and each sector for estimating LVEF and time to end systole (TES) . The differences of TES between whole LV and each sector were calculated and these 5 differences were averaged (Variation of TES) . We defined this Variation of TES as an index of LV asynchrony, and used for detection of CAD. The overall sensitivity and specificity for identifying CAD were 63% and 83% (LVEF during exercise) , 51% and 83% (ΔLVEF) . Variation of TES during exercise had a sensitivity and a specificity of 88% and 83% , and was more sensitive than both LVEF during exercise and ΔLVEF (p<0.01) . In conclusion, Variation of TES was a good marker of LV asynchrony and useful for the detection of CAD. |
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| Practice | Clinical medicine |
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| Keywords | First-pass radionuclide ventriculography, Coronary artery disease, Sector analysis |
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