| Japanese |
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| Title | 111In-Antimyosin F abを用いた心筋イメージングによる心筋壊死の評価 |
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| Subtitle | 原著 |
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| Authors | 西村恒彦*, 三谷勇雄*, 岡尚嗣*, 林田孝平*, 植原敏勇*, 汲田伸一郎*, 起塚裕美*, 山上英利*, 林真*, 土師一夫**, 河瀬吉雄**, 住吉徹哉**, 永田正毅** |
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| Authors(kana) | |
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| Organization | *国立循環器病センター放射線診療部, **心臓内科 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 9 |
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| Page | 1149-1159 |
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| Year/Month | 1989/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」111In-antimyosin F abによる心筋イメージングを用いて, 急性心筋梗塞13例, および心筋炎, 心筋症9例にて臨床的評価を行った. 111In-antimyosin F ab 74 MBq (2mCi) 静注2日後にさらに201TlCl 74 MBq (2mCi) 静注を行い, 2核種同時収集Planar, SPECTを施行した. 急性心筋梗塞13例中12例 (92%) に梗塞部位に一致して111In-antimyosin F abの陽性描出を認めた. 高度集積例は, PTCR/PTCAを施行した症例に多かった. 201TlClとの併用により下後壁梗塞の検出が容易になり, 陳旧性梗塞との鑑別が可能であった. 2核種同時収集SPECTにより, 201TlClとの心筋灌流を比較することにより詳細な梗塞心筋性状の評価が行えた, 心筋炎, 心筋症では9例中7例 (77%) にびまん性の陽性描出を認めた. 本法は, 発症10日前後の心筋梗塞で鮮明に陽性像として描出され, また徐々に崩壊する心筋壊死の検出にも有効であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | 111In-antimyosin, 201TlCl, Acute myocardial infarction, Myocarditis, Dilated cardiomyopathy |
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| English |
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| Title | Assessment of Myocardial Necrosis by 111In-Antimyosin F ab Scintigraphy |
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| Subtitle | Original Articles |
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| Authors | Tsunehiko NISHIMURA*, Isao MITANI*, Hisashi OKA*, Kohei HAYASHIDA*, Toshiisa UEHARA*, Shinichiro KUMITA*, Hiromi OKIZUKA*, Hidetoshi YAMAGAMI*, Makoto HAYASHI*, Kazuo HAZE**, Kichio KAWASE**, Tetsuya SUMIYOSHI**, Seiki NAGATA** |
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| Authors(kana) | |
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| Organization | *Department Radiology, **Department of Cardiology, National Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 9 |
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| Page | 1149-1159 |
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| Year/Month | 1989/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 111In-antimyosin F ab (AM) myocardial scintigraphy was carried out in (A) 13 patients with acute myocardial infarction (9.9+-2.2 days from the onset) and (B) 9 with myocarditis and/or dilated cardiomyopathy. Forty eight hours after injection of AM, the patients were injected with 74 MBq (2 mCi) of thallium-201 (TL) . The two sets of Planar and SPECT image were obtained simultaneously using dual energy window sets. In group A, positive focal AM uptake was demonstrated in 12 (92%) patients. Higher AM uptake was observed in patients who had PTCR/PTCA. By combination with TL, it is useful to detect inferior infarction and to differentiate old from acute infarction. Dual SPECT images gave precise information about the infarcted area. In group B, positive diffuse AM uptake was demonstrated in 7 (77%) patients. In conclusion, AM myocardial scintigraphy was proven to be useful for the assessment of acute necrosis after myocardial infarction but also on-going necrosis of myocarditis and/or myopathy. |
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| Practice | Clinical medicine |
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| Keywords | 111In-antimyosin, 201TlCl, Acute myocardial infarction, Myocarditis, Dilated cardiomyopathy |
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