| Japanese |
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| Title | Ga-67の体内分布に及ぼす鉄代謝の影響について |
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| Subtitle | ≪原著≫ |
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| Authors | 東光太郎*, 松田昌夫*, 大津留健*, 高瀬秀子*, 上村吉郎**, 関宏恭*, 大口学*, 興村哲郎*, 宮村利雄*, 山本達* |
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| Organization | *金沢医科大学放射線医学教室, **二ツ屋病院 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 7 |
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| Page | 865-877 |
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| Year/Month | 1989/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」Ga-67の体内分布に及ぼす鉄代謝の影響について, 120症例(125件)のGa-67シンチグラフィを対象として検討した. 肝および腰椎の相対的なGa-67の摂取量(肝および腰椎のカウントを大腿部軟部組織のカウントで除した値)は, 血清鉄値と負の相関関係を, またUIBCと正の相関関係を示した. またGa-67の腰椎への分布パターンの差異より, 血清鉄低値群(UIBC高値群)では主に骨髄に, 血清鉄高値群(UIBC低値群)では主に骨にGa-67が集積することが推測された. Ga-67静注48時間後の腎の描出率は, 血清鉄高値群が血清鉄正常域群よりも有意に高率となった. また膀胱の描出は, 血清鉄高値群においてのみ認められた. このことより. 血清鉄高値(UIBC低値)の場合はGa-67の尿中排泄が延長することが示唆された. これらのGa-67の体内分布, 特に肝の相対的なGa-67の摂取量から, 鉄代謝の状態を推定することが可能であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Ga-67 distribution, Ferric metabolism, Serum Fe, UIBC. |
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| English |
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| Title | The Influence of Ferric Metabolism on Ga-67 Distribution in Human Body |
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| Subtitle | - Original Articles - |
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| Authors | Koutarou HIGASHI*, Masao MATSUDA*, Takeshi OHOTSURU*, Syuuko TAKASE*, Yoshirou KAMIMURA**, Hiroyasu SEKI*, Manabu OHOGUCHI*, Tetsurou OKIMURA*, Toshio MIYAMURA*, Itaru YAMAMOTO* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Kanazawa Medical University, **Futatsuya Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 7 |
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| Page | 865-877 |
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| Year/Month | 1989/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] This investigation was undertaken to make clear the influence of ferric metabolism on Ga-67 distribution in human body. Count ratios for each organ to femoral soft tissue (i.e. relative Ga-67 uptake) were calculated in 125 scintigrams obtained 48 hours following injection, and the relation between the relative Ga-67 uptake in each organ and serum Fe, or UIBC were investigated. The relative Ga-67 uptake in the liver and the lumbar vertebra had negative correlation to serum Fe, and had positive correlation to UIBC. However, there was no significant difference in the relative Ga-67 uptake in the lumbar vertebra between normal and high serum Fe group. Only in group with exceedingly low serum Fe, each vertebral body was visualized separately in posterior view of the abdomen. These findings indicated that in group with exceedingly low serum Fe, Ga-67 accumulated mainly in the bone marrow, and in group with high serum Fe, Ga-67 accumulated mainly in the bone. The urinary bladder was visualized only in group with high serum Fe, which suggested that the excretion of Ga-67 to the urine was continued yet at 48 hours after injection. Ferric metabolism affected remarkably on the relative Ga-67 uptake in the liver, the bone marrow and the bone, and also the excretion of Ga-67 to the urine. |
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| Practice | Clinical medicine |
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| Keywords | Ga-67 distribution, Ferric metabolism, Serum Fe, UIBC. |
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