| Japanese |
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| Title | 陰性dipyridamole負荷心筋シンチの臨床的意義 |
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| Subtitle | ≪原著≫ |
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| Authors | 楠目修*,†, 浜重直久*,†, 米沢嘉啓*, 土居義典*, 小田原弘明*, 近森大志郎*, 小澤利男*, 赤木直樹**, 吉田祥二**, 前田知穂** |
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| Organization | *高知医科大学老年病科, **放射線科, †現近森病院循環器科 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 6 |
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| Page | 753-762 |
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| Year/Month | 1989/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」Dipyridamole負荷心筋シンチを施行した671例について, 欠損像陰性の242例(A群)と陽性の429例(B群)に大別し, 冠動脈造影所見や予後などを比較し, 陰性シンチグラムの信頼性や臨床的意義を検討した. 1)冠動脈造影による有意病変(>50%内径狭窄)は, B群285例中235例(82%)に対してA群92例中7例(8%)にみられた. うち多枝病変はそれぞれ119例(42%)・2例(2%)であった. 2)初期血行再建例(B群の52例)を除く619例中, 平均29か月の薬物治療で, 48例(8%)の心臓死と19例(3%)の非致死的心合併症を認めた. これら心合併症は, B群377例中60例(16%)に対してA群242例中7例(3%)にみられ, うち心臓死はそれぞれ44例(12%)・4例(2%)であった. 以上, dipyridamole負荷心筋シンチ陰性例では, 重症器質的冠狭窄は稀で予後も比較的良好であり, 対症的薬物療法に抵抗する例を除いて冠動脈造影は不要と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Dipyridamole perfusion scintigraphy, Negative scintigram, Coronary angiography, Prognosis. |
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| English |
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| Title | Clinical Significance of Negative Dipyridamole Perfusion Scintigram |
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| Subtitle | - Original Articles - |
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| Authors | Osamu KUZUME*, Naohisa HAMASHIGE*, Yoshihiro YONEZAWA*, Yoshinori DOI*, Hiroaki ODAWARA*, Taishiro CHIKAMORI*, Toshio OZAWA*, Naoki AKAGI**, Shoji YOSHIDA**, Tomoho MAEDA** |
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| Authors(kana) | |
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| Organization | *Section of Cardiology, Department of Medicine and Geriatrics, Kochi Medical School, **Department of Radiology, Kochi Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 6 |
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| Page | 753-762 |
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| Year/Month | 1989/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Six hundred seventy-one patients who had dipyridamole perfusion scintigraphy were classified into two groups; ie, 242 patients without perfusion defect (Group A) and 429 patients with perfusion defect (Group B). Clinical significance of negative scintigram was then assessed and correlated with coronary angiographic findings and prevalence of cardiac events. 1) Significant coronary artery disease (>50% luminar narrowing) was present in 7 of 92 patients (8%) in Group A and in 235 of 285 patients (82%) in Group B. Multi-vessel coronary artery disease was found only in 2 patients (2%) in Group A and in 119 patients (42%) in Group B. 2) During a mean follow-up period of 29 months, 48 cardiac death (8%) and 19 nonfatal cardiac events (3%) occurred in 619 medically treated patients. These cardiac complications were observed in 7 of 242 patients (3%) in Group A and in 60 of 377 patients (16%) in Group B, including 4 (2%) and 44 (12%) cardiac deaths, respectively. In conclusion, it is rare to see severe organic coronary artery disease and future cardiac event in patients with negative dipyridamole perfusion scintigram. It may be, therefore, stated that it is unnecessary to perform coronary angiography in these patients, unless they have symptoms which cannot be controlled medically. |
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| Practice | Clinical medicine |
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| Keywords | Dipyridamole perfusion scintigraphy, Negative scintigram, Coronary angiography, Prognosis. |
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