Japanese
TitlePTCA成功後のトレッドミル運動負荷試験におけるST低下持続例の臨床的意義 - 201Tl運動負荷心筋SPECTによる評価 -
Subtitle≪原著≫
Authors青木俊和*, 小西得司*, 二神康夫*, 岡本紳也*, 小山孝夫*, 西村泰豪**, 位田正明*, 山門徹*, 浜田正行*, 中野赳*
Authors(kana)
Organization*三重大学医学部第一内科, **松阪中央病院内科
Journal核医学
Volume26
Number6
Page733-741
Year/Month1989/6
Article原著
Publisher日本核医学会
Abstract「要旨」待期的PTCA成功後のトレッドミル運動負荷試験においてST低下が持続する症例を対象にそのST低下の意義を明らかにするために201Tl運動負荷心筋SPECTにより比較検討した. 待期的PTCA成功1週後のトレッドミル試験でST低下をきたしたものは35例中14例(40%)に認められ, その後の検査でST低下が消失したのは3例(9%), それに対してST低下が3〜6か月後も遷延したのは11例(31%)であった. 再狭窄は後者のうちの6例に認められた. ST低下遷延例のうち, SPECTにおいて再狭窄例6例中5例に再分布が認められたが, 非再狭窄例およびST低下消失例ではいずれも再分布は認められなかった. PTCA後再狭窄がないのにST低下が遷延する症例はトレッドミル試験の偽陽性例と考えられSPECTの有用性が示された. 一方, ST低下が徐々に消失する例は, 今回の検討では明らかな原因を示唆する所見を得られず, 今後の検討を待たねばならない.
Practice臨床医学:一般
KeywordsThallium-201 myocardial SPECT, Treadmill exercise, PTCA, CAD.
English
TitleClinical Significance of Exercise Induced ST Segment Depression after Successful Percutaneous Transluminal Coronary Angioplasty - Assessment by Thallium-201 SPECT -
Subtitle- Original Articles -
AuthorsToshikazu AOKI*, Tokuji KONISHI*, Yasuo FUTAGAMI*, Shinya OKAMOTO*, Takao KOYAMA*, Yasuhide NISHIMURA**, Masaaki INDEN*, Tetsu YAMAKADO*, Masayuki HAMADA*, Takeshi NAKANO*
Authors(kana)
Organization*First Department of Internal Medicine, Mie University School of Medicine, **Internal Medicine, Matsuzaka Tyuou Hospital
JournalThe Japanese Journal of nuclear medicine
Volume26
Number6
Page733-741
Year/Month1989/6
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] To evaluate the clinical significance of ST segment depression during repeated Treadmill exercise after successful PTCA, Thallium-201 SPECT was performed. The Thallium-201 SPECT was performed before, one week after and 3-6 months after PTCA. All thirty-five patients had one vessel disease and positive Thallium-201 exercise test. During follow-up period for 3-6 months, 11 of 35 patients had persistent ST segment depression. Restenosis of dilated coronary lesion was demonstrated in 6 of 11 patients. In another 3 of 35 patients, exercise induced ST segment depression was disappered during follow-up Treadmill exercise. In 14 patients with persistent or transient ST segment depression after PTCA, Thallium-201 SPECT demonstrated transient ischemia in 5 of 6 patients with restenosis. In other 8 patients without restenosis, SPECT images did not demonstrate myocardial ischemia and coronary arteriographic findings could not verify side branch stenosis or intimal dissection which might cause myocardial ischemia. The etiology of ST segment depression after successful PTCA in one vessel disease is not produced by exercise induced myocardial ischemia but still unknown mechanisms may be present.
PracticeClinical medicine
KeywordsThallium-201 myocardial SPECT, Treadmill exercise, PTCA, CAD.

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