| Japanese |
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| Title | SPECTを用いた201Tlの洗い出し率マップによる虚血性心疾患の評価 |
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| Subtitle | ≪原著≫ |
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| Authors | 中嶋憲一*, 村守朗*, 滝淳一*, 分校久志*, 谷口充*, 南部一郎*, 松成一朗*, 久田欣一* |
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| Organization | *金沢大学医学部核医学科 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 5 |
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| Page | 617-623 |
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| Year/Month | 1989/5 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」201Tl心筋シンチグラフィにおいて洗い出し率(WR)は, 冠動脈疾患の評価に有用でありその重症度評価に用いられている. そこで201Tl心筋短軸断層像から作成した心筋血流の極座標型機能マップ(いわゆるBull's-eye表示)からWRのマップを計算した. さらに正常者群から, 局所WRの絶対値および相対値による2種類の標準値を作成した. おのおのの標準値を用いて, 異常の広がりおよび程度の指標であるextentおよびseverity scoreを算出した. 多重回帰によれば, 心筋全体ではWR(%)=-2.38×(狭窄動脈数)+0.093×(rate-pressure product/100)+19.7(n=62, r=0.63)であり, 絶対値のWRは運動量の影響を受けるため補正が必要である. 一方, 機能マップの異常スコアは相対値の標準値を用いたほうが, 絶対値を用いるより, 異なる狭窄冠動脈数の群を良く分離した. 以上より心筋全体としての絶対値のWRは冠動脈疾患の重症度評価に有用であるが, 機能マップの評価の際には, 相対的なWRの分布の評価のほうがむしろ適切であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Myocardial scintigraphy, 201Tl washout rate, Single-photon emission computed tomography (SPECT), Functional map, Coronary artery disease. |
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| English |
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| Title | Evaluation of Ischemic Heart Disease by Thallium-201 Washout-rate Map Using SPECT |
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| Subtitle | - Original Articles - |
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| Authors | Kenichi NAKAJIMA, Akira MURAMORI, Junichi TAKI, Hisashi BUNKO, Mitsuru TANIGUCHI, Ichiro NANBU, Ichiro MATSUNARI, Kinichi HISADA |
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| Authors(kana) | |
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| Organization | Department of Nuclear Medicine, Kanazawa University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 5 |
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| Page | 617-623 |
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| Year/Month | 1989/5 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In thallium-201 myocardial perfusion scintigraphy, washout rate (WR) has been used for the evaluation of the severity of ischemic heart disease (IHD). The WR was calculated from the polar map (Bull's-eye display) of myocardial perfusion using SPECT. To analyze the abnormality of WR map, we computed the extent and severity scores of WR. Applications of two types of standards, absolute and relative standards from control group (n=16),were compared. The multiple regression analysis showed that the global WR was a function of the severity of coronary artery stenosis and exercise level, i.e. WR (%) = -2.38×(number of stenotic artery) + 0.093×(rate-pressure product/100) + 19.7 (n=62, r=0.63). Thus in evaluating the severity of IHD by absolute WR, the correction of WR was necessary according to the exercise level. Whereas, to evaluate the score of WR abnormality in polar map, the relative standard separated each group with different number of stenotic artery better than absolute standard did. In conclusion, calculation of WR score from relative standard is recommended for the analysis of polar WR map, although absolute global WR is useful for the evaluation of severity of coronary artery disease. |
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| Practice | Clinical medicine |
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| Keywords | Myocardial scintigraphy, 201Tl washout rate, Single-photon emission computed tomography (SPECT), Functional map, Coronary artery disease. |
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