| Japanese |
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| Title | Xe-133肺換気シンチグラム洗いだし相の因子分析による不均等換気の診断 |
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| Subtitle | 原著 |
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| Authors | 本田憲業*, 町田喜久雄*, 間宮敏雄*, 高橋卓*, 瀧島輝雄*, 長谷川典子*, 釜野剛*, 大野研* |
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| Organization | *埼玉医科大学総合医療センター放射線科学教室 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 4 |
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| Page | 507-513 |
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| Year/Month | 1989/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 連続50例のXe-133肺換気シンチグラム洗いだし相に因子分析を施行し, 本法による肺内不均等換気の診断を, 洗いだし相動態シンチグラム診断と比較し, 検討した. 因子分析から肺内平均通過時間 (MTT) を求め, 高さ/面積法 (H/A) , および2コンパートメント法 (2C) によるMTTと比較した. 正常シンチグラム所見者12例では, 1因子はバックグラウンドを, もう1因子は左右各肺に均一に分布する洗いだしのコンパートメントを, それぞれ示した. 異常シンチグラム所見者38例中31例 (82%) で, 因子分析による遅延洗いだし部位とシンチグラム上の遅延洗いだし部位とは一致した. 5例 (13%) で因子分析の方が多数の遅延洗いだし部位を示した. 因子分析によるMTTは主に正常シンチグラム所見者でのみ2Cと相関したがH/Aとは相関しなかった. 因子分析は換気不均等分布の診断に有用と思われた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Ventilation scintigram, Factor analysis, Mean transit time, Xe-133, Washout |
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| English |
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| Title | Clinical Assessment of Uneven Ventilation by Factor Analysis of Xe-133 Washout Scintigram |
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| Authors | Norinari HONDA, Kikuo MACHIDA, Toshio MAMIYA, Taku TAKAHASHI, Teruo TAKISHIMA, Noriko HASEGAWA, Tsuyoshi KAMANO, Ken OHNO |
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| Authors(kana) | |
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| Organization | Department of Radiology, Saitama Medical Center, Saitama Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 4 |
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| Page | 507-513 |
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| Year/Month | 1989/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Factor analysis (FA) was applied to 50 consecutive Xe-133 washout lung scintigrams, and its findings were compared with dynamic scintigrams of Xe-133 washout (DSW) . Mean transit time (MTT) of radioactive xenon measured by FA also was compared with that measured by height/area (H/A) or two-compartment analysis (2CA) . In 12 patients with normal DSW, FA separated and located two factors : one represented background activity, and the other uniform washout from the lung. In 31 out of 38 patients (82%) with abnormal DSW, FA separated the same areas where the washout was delayed on DSW. In 5 (13%) patients, FA diagnosed more areas of delayed washout than DSW. FA failed in 2 (5%) patients, but this failure was due to small number of counts of pixels. Diagnosis by FA was seemed easier than diagnosis by DSW in 95% of all patients by the authors' impression. MTT by FA (y) correlated with MTT by 2CA (x) in small groups of patients : in 9 patients in whom only one MTT was obtainable by FA (r = 0.75, p = 0.02, y = 4.2x + 1.9) , and in 8 patients of normal DSW in whom two MTT's were obtainable by FA (r = 0.77, p = 0.02, y = 0.69x + 6.2, y ; shorter MTT by FA between the two) . MTT by FA did not correlate with MTT by H/A. In conclusion, FA is useful for diagnosing uneven Xe-133 washout from the lung. |
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| Practice | Clinical medicine |
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| Keywords | Ventilation scintigram, Factor analysis, Mean transit time, Xe-133, Washout |
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