| Japanese |
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| Title | テクネチウムピロリン酸心筋シンチグラフィSPECTによる心筋梗塞巣の定量的評価 |
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| Subtitle | 原著 |
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| Authors | 山本博道*, 福山尚哉*, 青木真*, 稲生哲治*, 芦原俊昭*, 鍋山庄蔵*, 山本雄祐* |
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| Organization | *松山赤十字病院循環器科 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 4 |
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| Page | 469-476 |
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| Year/Month | 1989/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 Technetium-99m pyrophosphate single photon emission computed tomography (99mTcPYP-SPECT) を用いて, 急性心筋梗塞巣の定量的評価を試みた. 16スライスしたSPECTデータから, 梗塞巣と胸郭の各voxel数を求め, その比を梗塞巣の大きさの指標とした. 貫壁性初回心筋梗塞患者41例について検討した. 前壁梗塞例では, 99mTcPYP-SPECTにより推定した梗塞巣の大きさと, ピークCPK値や201T1心筋シンチグラムSPECTのextent scoreとの間に有意の正相関を認めた. またRI心室造影法による急性期および慢性期の左室駆出率, 急性期から慢性期への左室駆出率の百分率変化等とも有意の負相関を認め, 心機能の予後推測に有用と考えられた. 一方, 下壁梗塞例ではいずれの検討項目についても有意の相関を得られず, 高率に含まれる右室梗塞合併の影響について検討が必要と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc pyrophosphate, Single photon emission computed tomography, Myocardial infarct size |
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| English |
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| Title | Quantification of Myocardial Infarct Size by Technetium-99m Pyrophosphate Single Photon Emission Computed Tomography |
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| Subtitle | Original Articles |
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| Authors | Hiromichi YAMAMOTO, Takaya FUKUYAMA, Makoto AOKI, Tetsuji INOU, Toshiaki ASHIHARA, Shyohzou NABEYAMA, Yuhsuke YAMAMOTO |
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| Authors(kana) | |
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| Organization | Cardiovascular Center, Matsuyama Red Cross Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 4 |
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| Page | 469-476 |
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| Year/Month | 1989/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Myocardial infarct size in 41 patients with the first attack of acute transmural myocardial infarction (MI) was assessed by technetium-99m pyrophosphate single photon emission computed tomography (99mTcPYP-SPECT) . A ratio of the number of voxels of 99mTcPYP uptake into the infarct area to that into the thorax was calculated as a parameter of MI size. The ratio was positively correlated with both peak CPK activity (r = 0.53, p < 0.005, n = 24) and extent score in 201T1-SPECT ( r = 0.70, p < 0.005, n = 14) significantly in patients with anterior MI but not in patients with inferior MI. There was also significant negative correlation between the ratio and the left ventricular ejection fraction (LVEF) measured by RI angiography in both acute (r = -0.67, p < 0.005, n = 18) and chronic (r = -0.75, p < 0.005, n = 25) phases in patients with anterior MI. Recovery in LVEF at chronic phase was noted in patients with small anterior MI but not with large anterior MI. 8 of 14 patients with inferior MI had right ventricular MI, that might have affected evaluation of MI size and resulted in no correlation between variables. It was suggested that 99mTcPYP-SPECT was a useful method to evaluate MI size and to predict prognosis of cardiac function in patients with anterior MI but not in patients with inferior MI. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc pyrophosphate, Single photon emission computed tomography, Myocardial infarct size |
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