| Japanese |
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| Title | タリウム201心筋polar mapによる虚血部および梗塞部における重症度と再分布の定量化 - 1枝病変についての検討 - |
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| Subtitle | 原著 |
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| Authors | 中西文子*, 春日敏夫*, 曽根脩輔**, 酒井康子**, 伊藤邦泰**, 山下公仁彦**, 小口和浩**, 佐々木康之***, 武田昌慶****, 矢野今朝人*, 横田憲一* |
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| Authors(kana) | |
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| Organization | *信州大学医学部附属病院放射線部, **放射線科, ***第二内科, ****第三内科 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 3 |
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| Page | 339-347 |
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| Year/Month | 1989/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 T1-201心筋polar mapを用いて冠動脈1枝病変66例における病変部心筋のviabilityを定量的に検討した. 正常人16例を対照とした. polar map上の病変部に関心領域を設定し, ここでの灌流の程度を正常領域内のカウントを基準とする initial % uptake (%Ui) と delayed % uptake (%Ud) で表し, 再分布の程度を%Ud/%Uiにより評価した. 対照群の%Uiは85.8士9.4, %Ud/%Uiは1.03土0.04であった. 再分布redistributionの認められた25例RD (+) では%Uiは51.5士13.3と低下し, %Ud/%Uiは1.37土0.26と増加を示した. 再分布の認められなかった41例RD (-) は2群, すなわち%Uiと%Ud/%Uiとが相関を示す17例RD (-) (1) と, 相関を示さない24例RD (-) (2) に分けられ, RD (-) (1) の%Uiは74.5±4.7と軽度低下を示し, RD (-) (2) では%Uiは31.7土8.7と高度低下を示したが%Ud/％Uiはこれら2群においては正常範囲にあった. 以上の結果から%Uiと%Ud/%Uiは心筋のviabilityについての指標として有用であると考えられた. これらのデータと冠動脈造影所見や左室造影所見との比較検討も行った. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium-201 SPECT, Polar map, Redistribution, Myocardial viability |
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| English |
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| Title | Quantification of Severity and Redistribution of Ischemic and Infarcted Myocardium by Thallium-201 Polar Map : Evaluation in Patients with Single Vessel Disease |
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| Authors | Fumiko NAKANISHI*, Toshio KASUGA*, Shusuke SONE*, Yasuko SAKAI*, Kuniyasu ITO*, Kunihiko YAMASHITA***, Kazuhiro OGUCHI*, Yasuyuki SASAKI**, Masayoshi TAKEDA***, Kesato YANO*, Kenichi YOKOTA* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **The Second Department of Internal Medicine, ***The Third Department of Internal Medicine, Shinshu University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 3 |
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| Page | 339-347 |
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| Year/Month | 1989/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Quantitative analysis of the polar map obtained from T1-201 single photon emission computed tomogram was employed to assess regional myocardial viability in 66 patients with single vessel coronary artery disease and 16 control subjects. Counts of region of interest in the stenotic and infarcted lesions and normal reference areas were calculated on the polar map. Severity of hypoperfused myocardium was determined as initial percent uptake (%Ui) and delayed percent uptake (%Ud) . Redistribution was analyzed as a ratio of %Ud to %Ui (%Ud/%Ui) . In the control group, the average %Ui was 85.8+-9.4 and %Ud/%Ui was 1.03+-0.04. Twenty five with reversible defect showed reduced %Ui (51.5+-13.3) and increased %Ud/%Ui (1.37+-0.26) . Fourty one cases with non-reversible defect were divided into two groups according to the value of %Ui. In the first group with a high %Ui (n = 17) , the average %Ui was 74.5+-4.7 and %Ud/%Ui was in normal range (1.06+-0.06) . In the second group (n = 24) , %Ui was most reduced (31.7+-8.7) , although %Ud/%Ui was in normal range (1.05+-0.17) . No significant correlation was shown between %Ui and %Ud/%Ui in the two groups with non-reversible defect. Correlation between %Ui and %Ud/%Ui was high (r = -0.76) in the group of reversible defect and the group of non-reversible defect with minimal reduced %Ui. It is concluded that the quantitative criteria obtained from polar map is valid to assess regional myocardial viability. The quantitative imaging data were also compared with coronary angiographic and left ventriculographic data. |
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| Practice | Clinical medicine |
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| Keywords | Thallium-201 SPECT, Polar map, Redistribution, Myocardial viability |
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