Japanese
Title肝動脈塞栓術による肝動脈血流の変化 - RIアンギオグラフィーによる検討 -
Subtitle原著
Authors水川帰一郎*, 佐藤功**, 日野一郎**, 瀬尾裕之**, 細川敦之**, 松野慎介**, 宮本勉**, 玉井豊理**, 田辺正忠**
Authors(kana)
Organization*住友別子病院放射線科, **香川医科大学医学部放射線科
Journal核医学
Volume26
Number3
Page319-328
Year/Month1989/3
Article原著
Publisher日本核医学会
Abstract「要旨」 経カテーテル動脈塞栓術 (TAE) を施行した肝腫瘍10症例のTAE前後に99mTc-phytateを用いて肝RIアンギオグラフィーを行い, 血流動態の変化を検討した. 肝臓および腹部大動脈に設定した関心領域 (ROI) より得られた時間放射能曲線の初期勾配の比 (RHA/A ratio) を局所肝動脈血流量の指標としてTAE前後で比較したところ, 腫瘍部あるいは腫瘍を含む範囲に設定したROIでは明らかな動脈血流減少が示されたが, 腫瘍を含まないROIでの減少は軽度であった. リピオドール単独注入の1例では肝動脈血流の減少は認められなかった. 同じ方法で求めた脾動脈血流の大動脈血流に対する比 (S/A ratio) はTAE前後で大きな差がなかったことから検査の再現性は良好と思われ, 本法はTAEによる肝動脈血流遮断効果の定量的評価に有用であると考えられた.
Practice臨床医学：一般
Keywords99mTc-phytate liver scintigraphy, Liver neoplasms, Transcatheter arterial embolization therapy
English
TitleScintigraphic Estimation of Dearterialization after Transcatheter Hepatic Arterial Embolization Therapy
Subtitle
AuthorsKiichiro MIZUKAWA*, Katashi SATOH**, Ichiro HINO**, Hiroyuki SEO**, Nobuyuki HOSOKAWA**, Shinsuke MATSUNO**, Tsutomu MIYAMOTO**, Toyosato TAMAI**, Masatada TANABE**
Authors(kana)
Organization*Department of Radiology, Sumitomo-Besshi Hospital, **Department of Radiology, Kagawa Medical School
JournalThe Japanese Journal of nuclear medicine
Volume26
Number3
Page319-328
Year/Month1989/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Radionuclide angiography was performed by bolus injection of 99mTc-phytate in 10 patients with liver neoplasms before and after the transcatheter hepatic arterial embolization therapy. The ratio of the slopes of the upstrokes for the hepatic arterial and abdominal aortic first transit curves constitutes the regional hepatic arterial to aortic blood flow ratio (RHA/A ratio) , which represents quantitatively the arterial blood flow of hepatic region of interest as a fraction of aortic blood flow. The degree of embolic dearterialization was estimated by the change of this ratio derives from the same region of interest for each patient before and after the embolization. The values and post-embolic reduction of the ratio correlated well individually with the angiographic features and other patients' data. The arterial blood supply to the tumor could not be reducted using Lipiodol alone as the embolic material in only 1 case. The finding that the splenic arterial to aortic blood flow ratio (S/A ratio) , calculated in the same way, was practically unchanged after the hepatic arterial embolization indicates the good reproducibility of these measurements. This noninvasive method may be helpful to evaluate the therapeutic effect of hepatic arterial embolization.
PracticeClinical medicine
Keywords99mTc-phytate liver scintigraphy, Liver neoplasms, Transcatheter arterial embolization therapy

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