Japanese
TitleN-isopropyl-p-[123I]iodoamphetamine (IMP) シンチグラフィ : 三次元表示法の有用性
Subtitle原著
Authors笠井俊文*, 杉村和朗*, 起塚裕美*, 石田淳*, 藤田安彦*, 古川珠見*, 杉原正樹*, 児玉光史*, 安井清*, 田中寛*, 石田哲哉*
Authors(kana)
Organization*島根医科大学放射線科
Journal核医学
Volume26
Number3
Page311-317
Year/Month1989/3
Article原著
Publisher日本核医学会
Abstract「要旨」 脳血管障害の診断におけるN-isopropy-p-[123I]iodoamphetamine (IMP) 三次元表示シンチグラフィの有用性を検討した. 脳血管障害15例, 正常7例を検討対象とした. 三次元像はSPECT水平断を基にStarcam (GE社) を用いてThreshold値50%で作成した. 読影経験5年以上 (経験者群) 3名, 読影経験2年以下 (未経験者群) 5名を読影者としてSPECT二次元像と三次元像の臨床評価をROC解析を用いて行った. SPECT二次元像の診断能は経験者群が未経験者群に比べて有意に優れていた. 一方, 三次元像では経験者群と未経験者群の間に統計学的に有意な差を認めなかった. また三次元像により読影者間に存在した診断能のばらつきが減少した. 本法は完全自動化・高速化されており少ない負担で診断能向上が期待できる有用なIMP脳シンチグラフィ表示法である.
Practice臨床医学:一般
KeywordsThree-dimensional imaging, 123I-IMP SPECT, Three-dimensional display, Computer graphics, 123I-IMP
English
TitleClinical Usefulness of Three-Dimensional Brain Imaging with N-isopropyl-p[123I]iodoamphetamine (IMP)
Subtitle
AuthorsToshifumi KASAI, Kazuro SUGIMURA, Hiromi OKIZUKA, Jun ISHIDA, Yasuhiko FUJITA, Tamami FURUKAWA, Masaki SUGIHARA, Kouji KODAMA, Kiyoshi YASUI, Hiroshi TANAKA, Tetsuya ISHIDA
Authors(kana)
OrganizationDepartment of Radiology, Shimane Medical University
JournalThe Japanese Journal of nuclear medicine
Volume26
Number3
Page311-317
Year/Month1989/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Three-dimensional reconstruction from N-isopropyl-p-[123I]iodoamphetamine (IMP) tomography has been applied clinically to the detection of perfusion defects in 22 cases (15 cerebrovascular diseases and 7 normal controls confirmed by CT and MRI) , with data being analyzed in terms of receiver operating characteristic curves (ROC) . The results showed that three-dimensional (3-D) image could make better diagnostic capability especially in unexperienced examiner and that it was useful indecreasing of difference of diagnostic capability. 3-D image could be taken within 1 minute and 15 seconds. We concluded that the three-dimensional brain imaging with IMP using this system was clinically useful because examiner could easily diagnose perfusion defects.
PracticeClinical medicine
KeywordsThree-dimensional imaging, 123I-IMP SPECT, Three-dimensional display, Computer graphics, 123I-IMP

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