| Japanese |
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| Title | 携帯用RI心機能モニター (VEST) による虚血性心疾患患者の日常動作を含む種々の運動時心機能の評価 |
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| Subtitle | 原著 |
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| Authors | 大嶽達*, 渡辺俊明*, 小坂昇*, 百瀬敏光*, 西川潤一*, 飯尾正宏*, 川久保清**, 戸田為久**, 杉本恒明** |
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| Authors(kana) | |
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| Organization | *東京大学医学部放射線科, **第二内科 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 2 |
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| Page | 195-212 |
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| Year/Month | 1989/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 携帯用RI心機能モニター(VEST)を用いて, 15症例の虚血性心疾患患者および対照の3例を対象として日常動作を含む各種運動負荷時心機能を評価した. その結果, VESTを用いて駆出分画(EF)の変化から負荷時一過性虚血を鋭敏に検出できた. 虚血性心疾患患者をトレッドミル運動負荷に対するEFの反応から4グループに分類したが, TI-201心筋SPECTでの再分布領域の広さや冠動脈病変の重症度と良く相関し, 冠動脈病変の重症度を本分類からある程度予測できた. 日常動作(歩行や階段上昇)に対する運動耐容能もこのグループ分類から予測できた. 左室拡張終期容積は座位や各種運動負荷で立位に比し各グループで増加し, 各グループ間に差はなかった. 心拍出量の増加率は各グループ間で明らかな差があり, 運動時心機能の有用な指標となると考えた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Technetium-99m red blood cell, Ventricular function, Ejection fraction, Gated blood pool study, Coronary artery disease |
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| English |
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| Title | Cardiac Response during Various Activities in Patients with Ischemic Heart Disease Evaluated by an Ambulatory Ventricular Monitor (VEST) |
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| Subtitle | |
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| Authors | Tohru OHTAKE*, Toshiaki WATANABE*, Noboru KOSAKA*, Toshimitsu MOMOSE*, Junichi NISHIKAWA*, Masahiro IIo*, Kiyoshi KAWAKUBO**, Iku TODA**, Tsuneaki SUGIMOTO** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **The Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 2 |
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| Page | 195-212 |
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| Year/Month | 1989/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To assess the cardiac response to various exercise in ischemic heart disease (IHD), left ventricular function was continuously measured with an ambulatory ventricular monitor (VEST) in 3 normal subjects and 15 IHD patients. Treadmill exercise (early stage (E1), end stage (E2) and recovery standing state (RE)), walking (WK) and climbing stairs (CS), was used for exercise. 15 IHD patients were divided into 4 groups by the LVEF response to treadmill exercise. In group 1 (G1), LVEF increased gradually at stage 1 and became plateau from stage 2 to end stage like normal group. In group 2 (G2), LVEF increased at stage 1 and became plateau from stage 2 but decreased from maximal EF more than 5% at end stage. In group 3 (G3), LVEF increased only at stage 1 and decreased immediately after stage 1 to end stage. The decrease of LVEF at end stage from standing was more than 5%. In group 4 (G4), LVEF decreased at stage 1 and became minimum at end stage. This grouping was well related to thallium redistribution (Tl RD) score and coronary arteriography (CAG) score. We could predict the severity of coronary artery disease from this grouping because all group 3 or 4 patients had severe coronary artery disease. VEST was useful for the evaluation for the tolerance to daily activities. Group 1, 2 and 3 tolerated daily activities while group 4 could not always. The degree of the increase in cardiac output during ischemia evaluated by VEST may be one of the useful index of the tolerance to exercise. In conclusion VEST was very useful for evaluating cardiac capacity of ischemic heart disease patients during various exercise. |
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| Practice | Clinical medicine |
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| Keywords | Technetium-99m red blood cell, Ventricular function, Ejection fraction, Gated blood pool study, Coronary artery disease |
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