| Japanese |
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| Title | 心腔, 肺における99mTc-アルブミン分布率の臨床的意義 |
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| Subtitle | 原著 |
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| Authors | 藤井忠重*, 金井久容*, 田中正雄*, 河野純*, 広瀬芳樹*, 平山二郎*, 本郷実*, 山田博美*, 大久保信一*, 半田健次郎*, 矢野今朝人** |
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| Authors(kana) | |
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| Organization | *信州大学医学部第一内科, **附属病院中央放射線部 |
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| Journal | 核医学 |
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| Volume | 26 |
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| Number | 1 |
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| Page | 23-33 |
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| Year/Month | 1989/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 各種心肺疾患において, 99mTc-アルブミンの心プールシンチグラフィを利用して, 右房・右室(RV), 左室(LV), 心・大血管系(CV)および肺(Lu)などの99mTc分布率を算出し, その臨床的意義を検討した. 対照, 肺性心, 左心不全(+)の心疾患の99mTc分布率はRVが3.4±O.6%, 6.0±0.8%, 7.9±1.7%, LVが3.1±0.5%, 2.6±0.8%, 7.7±3.5%, CVが10.4±2.0%, 14.2±2.4%, 20.7±4.3%であった. LVの99mT分布率は心室造影による拡張終期容積と相関(r=0.72)を示した. RVとLVの99mTc分布率はともにNYHA心機能分類との関連を認めた. Luの99mTc分布率は対照4.9±1.4%, 肺性心4.4+1.1%, 左心不全(-)の心疾患6.6±1.9%であった. 本法は心室腔と肺における血液量の指標を同時かつ簡易に算出でき, 心疾患の病態を評価するうえで役立つ. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-albumin, Cardiac pool scintigram, 99mTc-albumin distribution ratio, Ventricular volume, Pulmonary blood volume |
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| English |
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| Title | Evaluation of 99mTc-Albumin Distribution Ratio in Cardiac Chambers and Lungs |
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| Authors | Tadashige FUJII*, Hisakata KANAI*, Masao TANAKA*, Jun KONO*, Yoshiki HIROSE*, Jiro HIRAYAMA*, Minoru HONGO*, Hiromi YAMADA*, Shinichi OKUBO*, Kenjiro HANDA*, Kesato YANO** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, Shinshu University School of Medicine, **Division of Radiology, Shinshu University Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 26 |
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| Number | 1 |
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| Page | 23-33 |
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| Year/Month | 1989/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In order to assess blood volume of the cardiac chambers and lungs, distribution ratio of 99mTc-albumin (HSA) was obtained from radionuclide angiocardiogram and non-gated or gated equilibrium cardiac pool scintigram, using a scintillation camera coupled to a minicomputer. The radioactivity of 99mTc of the entire cardiac blood pool including the large vessels (T), the right ventricle including the right atrium (RV) and the left ventricle (LV) was calculated from the 30° anterior oblique cardiac pool scintigram. That of the both lungs (Lu) was calculated from the anterior cardiac pool scintigram. The radioactivity of total injected dose of HSA (H) was estimated from the initial transit of the tracer obtained by the radionuclide angiocardiogram. Then, distribution ratio of HSA of the each region of interest was expressed as RV/H, LV/H, T/H and Lu/H. RV/H, LV/H and T/H were 3.4+-0.6%, 3.1+-0.5% and 10.4+-2.0% in controls, 6.0+-0.8%, 2.6+-0.8% and 14.2+-2.4% in cor pulmonale, and 7.9+-1.7%, 7.7+-3.5% and 20.7+-4.3% in heart diseases with left heart failure, respectively. Lu/H was 4.9+-1.4% in controls, 4.4+-1.1% in corpulmonale and 6.6+-1.9% in heart diseases without left heart failure. LV/H was correlated with left ventricular end-diastolic volume by contrast ventriculography. LV/H and RV/H were related with functional classification of NYHA. In conclusion, these parameters may be utilized as indices of the volume of blood pool of the heart chambers and lungs, and this method seems to be clinically applicable for the evaluation of pathophysiology in heart diseases. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-albumin, Cardiac pool scintigram, 99mTc-albumin distribution ratio, Ventricular volume, Pulmonary blood volume |
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