| Japanese |
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| Title | 原発性肺癌が疑われた患者におけるTl-201 Single photon emission computed tomographyの臨床的検討 |
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| Subtitle | 原著 |
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| Authors | 利波紀久*, 秀毛範至*, 関宏恭**, 高山輝彦***, 滝鈴佳*, 横山邦彦*, 松本隆裕*, 絹谷清剛*, 渡辺直人*, 瀬戸幹人*, 道岸隆敏*, 油野民雄*, 久田欣一*, 渡辺洋宇**** |
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| Authors(kana) | |
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| Organization | *金沢大学医学部核医学数室, **金沢医科大学放射線医学教室, ***金沢大学医療技術短期大学部, ****医学部第一外科教室 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 12 |
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| Page | 1381-1394 |
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| Year/Month | 1988/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 原発性肺癌が疑われた30例にTl-201 SPECTのEarly scanとDelayed scanを施行した. 原発性肺癌21例を含む肺悪性腫瘍23例の肺病巣すべてに異常集積を認めた. 1.5×1.0×1.5cmの原発性肺癌が明瞭に描出された. 良性病巣は7例中2例のみに異常集積を認めた. Delayed scanで求めた, 病巣と対側健常肺の集積比では原発性肺癌と良性病巣の間に有意差(p<0.01)を認めた. また, Early scanとDelayed scanの比較から求めたRetention Indexでも原発性肺癌と良性病巣の間に有意差(p<0.05)を認めた. 開胸手術を受けた原発性肺癌17例で縦隔リンパ節転移の有病正診率は71%, 無病正診率80%, 正診率76%であった. 有病誤診例はいずれも1cm以下の病巣であり, 有病正診例の最小病巣は直径1.5cmであった. 本法は肺病巣の良性, 悪性の鑑別と肺癌縦隔リンパ節転移の診断にきわめて有用であると思われる. |
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| Practice | 臨床医学：一般 |
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| Keywords | Tl-201 chloride, Single photon emission computed tomography, Bronchogenic carcinoma |
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| English |
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| Title | Clinical Evaluation of Tl-201 Single Photon Emission Computed Tomography in Patients with Suspected Bronchogenic Carcinoma |
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| Authors | Norihisa TONAMI*, Noriyuki SHUKE*, Hiroyasu SEKI**, Teruhiko TAKAYAMA***, Suzuka TAKI*, Kunihiko YOKOYAMA*, Takahiro MATSUMOTO*, Seigo KINUYA*, Naoto WATANABE*, Mikito SETO*, Takatoshi MICHIGISHI*, Tamio ABURANO*, Kinichi HISADA*, Yoh WATANABE**** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine, ****The First Department of Surgery, Kanazawa University School of Medicine, **Department of Radiology, Kanazawa Medical University, ***School of Allied Medical Professions |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 12 |
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| Page | 1381-1394 |
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| Year/Month | 1988/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Single photon emission computed tomography (Early scan and Delayed scan) was performed using 8-10mCi of Tl-201 chloride in 30 patients with suspected bronchogenic carcinoma. An abnormal uptake was observed in all of 23 malignant lung lesions including 21 bronchogenic carcinomas. A small primary lesion of 1.5×1.0×1.5cm was clearly visualized. Two of 7 benign conditions showed positive Tl-201 studies. In the Tl-201 uptake ratio per voxel of the lesion to the opposite normal lung in the Delayed scan, there was a significant difference between bronchogenic carcinoma and benign condition (p<0.01). In the Tl-201 Retention Index which was obtained from both Early and Delayed scans, there was a significant difference between bronchogenic carcinoma and benign condition (P<0.05). In the detection of mediastinal metastases from bronchogenic carcinoma on Tl-201 Delayed scan true positive was 71%(5/7). The smallest lesion was 1.5cm in diameter. Two patients with false negative had small metastases less than 1.0cm in diameter. Two of 10 patients without mediastinal metastasis showed false positive. Our results show that Tl-201 SPECT provides excellent sensitivity in the detection of malignant pulmonary lesions and can effectively differentiate malignant lesions from benign conditions and can be also used in the diagnosis of mediastinal metastases from bronchogenic carcinoma. |
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| Practice | Clinical medicine |
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| Keywords | Tl-201 chloride, Single photon emission computed tomography, Bronchogenic carcinoma |
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