| Japanese |
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| Title | 悪性黒色腫におけるGa-67とI-123IMPの比較検討 |
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| Subtitle | 原著 |
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| Authors | 久保公三*, 伊藤和夫**, 中駄邦博**, 塚本江利子**, 古舘正從**, 杉原平樹***, 星光聡*** |
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| Authors(kana) | |
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| Organization | *北海道大学医学部放射線科, **核医学科, ***形成外科 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 12 |
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| Page | 1329-1335 |
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| Year/Month | 1988/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 脳血流測定用放射性薬剤として開発されたI-123IMPははやくから悪性黒色腫への集積の可能性が言われていた. 一方, 悪性黒色腫はGa-67の良く集積する腫瘍として知られていた. そこでわれわれは両者による検査を14症例に施行し, 術前検査の5例(A群), 術後のfollow up検査の9例(B群), の2群に分けて比較検討を加えた. 投与量はI-123IMPが3mCi, Ga-67が2mCiで両者ほぼ同時期に施行した. その結果, A群では原発巣および転移巣(所属リンパ節)の検出能はI-123IMPがGa-67より優れていた. B群ではI-123IMPで胸部(肺)の病変を指摘しえなかったほかは両者とも良好な結果を示した. また両検査の併用はより有効であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | I-123 IMP, Gallium-67 citrate, Melanoma |
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| English |
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| Title | The Comparative Study with Ga-67 and I-123 IMP in Malignant Melanoma |
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| Subtitle | |
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| Authors | Kouzou KUBO*, Kazuo ITOH**, Kunihiro NAKADA**, Eriko TSUKAMOTO**, Masayori FURUDATE**, Hiraki SUGIHARA***, Mitsusato HOSHI*** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Nuclear Medicine, ***Department of Plastic Surgery, Hokkaido University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 12 |
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| Page | 1329-1335 |
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| Year/Month | 1988/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] N-isopropyl-p-[123I]iodoamphetamine (I-123 IMP) is a radiopharmaceutical for brain blood perfusion imaging and also has potential as a melanoma seeker. On the other hand, the utility of Ga-67 citrate imaging for the detection of melanoma has been well documented. Both I-123 IMP and Ga-67 scintigraphies were performed in 14 cases with melanoma in order to compare their clinical utility in the same patient. To assess the results of this study, we attemped to divide the patients into two groups : five preoperative patients(Group A) and nine postoperative patients(Group B). The results were as follows : 1. I-123 IMP scan is more effective than that of Ga-67 for demonstrating both primary site and lymph node metastases in a preoperative group. 2. I-123 IMP scan did not detected lung metastases in postoperative patients for its normal activity in the lung, but Ga-67 scan demonstrated abnormal uptake in the lung suggestive of metastases in the same patient. I-123 IMP and Ga-67 were well accumulated in the other lesions except the lung. 3. It is useful to perform both methods for the detection of melanoma. |
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| Practice | Clinical medicine |
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| Keywords | I-123 IMP, Gallium-67 citrate, Melanoma |
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