Japanese
TitleTl-201運動負荷心筋シンチグラフィーによる冠側副血行路の意義
Subtitle原著
Authors加納康至*, 塩谷英之*, 前田和美**, 福崎恒*
Authors(kana)
Organization*神戸大学医学部第一内科, **医療技術短期大学部
Journal核医学
Volume25
Number11
Page1271-1278
Year/Month1988/11
Article原著
Publisher日本核医学会
Abstract「要旨」 冠側副血行の意義を明らかにする目的で, 血流を冠側副血行に全面的に依存する冠動脈の完全閉塞下領域についてTl動態を解析した. 対象は冠動脈に完全閉塞を有し, その灌流域に虚血部が存在する労作性狭心症23例で, 冠側副血行の発達程度の良好なI群(n=13)と不良なII群(n=10)に分類した. 方法は既報のTl 2回分注運動-NTG負荷法で行い, 運動負荷直後(Ex-1像), 20分後(Ex-2像), NTG投与後(NTG像)の各Imageで関心領域を設定し, 正常心筋に対する相対比を求めた. (1) Ex-1像における相対比はI群75.8±3.5%, II群77.2±2.9%であり, NTG像ではI群97.3±3.1%, II群96.4±5.2%と両群間に差は認められず両群は同程度の虚血を有すると考えられた. (2) しかしEx-2像ではI群85.3±4.7%対しII群79.3±3.9%と有意にI群が高く(P<0.005), またNTG像を基準とした場合のEx-2像での回復率はI群45.8±19.7%, II群12.4±10.1%とI群で高値であった(p<0.005). 以上の結果より良好な冠側副血行は, 心筋虚血からの回復過程を速やかにすることが示唆された.
Practice臨床医学:一般
KeywordsEffort angina pectoris, Collateral vessels, Thallium-201 myocardial scintigraphy
English
TitleAssessment of the Significance of Coronary Collateral Vessel by Using Thallium-201 Myocardial Imaging
Subtitle
AuthorsYasushi KANOH*, Hideyuki SHIOTANI*, Kazumi MAEDA**, Hisashi FUKUZAKI*
Authors(kana)
Organization*Department of Internal Medicine Devision I, Kobe University School of Medicine, **School of Allied Medical Sciences, Kobe University
JournalThe Japanese Journal of nuclear medicine
Volume25
Number11
Page1271-1278
Year/Month1988/11
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] For functional assessment of coronary collateral vessels, twenty-three patients with effort angina pectoris who had total coronary obstruction were studied. The patients were divided depending on the degree of development of collateral vessels into two groups, i. e. good collateral group I(n=13) and poor collateral group II(n=10). Thallium-201 scan was performed immediately (Ex-1 image), 20 minutes (Ex-2 image) after exercise and after nitroglycerin administration (NTG image) respectively. In all images, the relative percent activity of thallium-201 in the collateral-dependent ischemic area to the normal myocardium were calculated and were compaired between two groups. Relative percent activities in group I and II were as follows : Ex-1 image;75.8+-3.5% vs. 77.2+-2.9%(NS), Ex-2 image;85.3+-4.5% vs. 79.3+-3.9%(p<0.005), NTG image;97.3+-3.1% vs. 96.4+-5.2%(NS). From these results, it was elucidated that good collateral induced early partial redistribution in its perfusion area, suggesting that good collateral circulation may provide rapid recovery from myocardial ischemia.
PracticeClinical medicine
KeywordsEffort angina pectoris, Collateral vessels, Thallium-201 myocardial scintigraphy

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