| Japanese |
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| Title | Indium-111 Oxineによる血小板シンチグラフィーの臨床的評価 |
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| Subtitle | 原著 |
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| Authors | 石川演美*, 武田徹*, 中島光太郎*, 佐藤始広*, 秋貞雅祥*, 井島宏** |
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| Authors(kana) | |
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| Organization | *筑波大学臨床医学系放射線医学, **外科学 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 11 |
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| Page | 1245-1254 |
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| Year/Month | 1988/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 血栓を伴う各種疾患112例に対し血小板シンチグラフィーを施行し, その臨床的有用性を検討した. 大動脈瘤における陽性率は80.0%と高かったが, 動脈瘤の年齢とは相関はみられなかった. 部位別に胸部, 胸腹部, 腹部に分けてみると, 胸部大動脈瘤での集積は比較的弱いことがわかった. 中小動脈の動脈瘤, 大動脈炎症候群, 深部静脈血栓症でも高い陽性率を認め, 血小板シンチグラフィーはこれらの血栓の診断にも有用であった. また心腔内血栓症では心エコーグラフィーとの間に相補的有用性を認めた. 標識にはIn-111を使用したが, 方法は容易でほぼ一定の高い標識率が得られた. 血小板シンチグラフィーは血小板の活動性を示唆しており, これらの血栓性疾患が内科的または外科的に治療される場合にはその効果判定や経過観察に有用な情報を与えると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 111In-oxine, Platelet, Aortic aneurysm, Thrombosis, Platelet function |
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| English |
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| Title | Clinical Evaluation of the Platelet Scintigraphy Using Indium-111 Oxine |
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| Authors | Nobuyoshi ISHIKAWA*, Tohoru TAKEDA*, Kohtaroh NAKAJIMA*, Motohiro SATOH*, Masayoshi AKISADA*, Hiroshi IJIMA** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Surgery, Institute of Clinical Medicine, University of Tsukuba |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 11 |
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| Page | 1245-1254 |
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| Year/Month | 1988/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The clinical usefulness of autologous platelets labeled with Indium-111 oxine was evaluated by scintigraphy as a diagnostic procedure for the detection of various thrombotic disorders as well as in different aneurysms. The positivity was found to be satisfactory (80.0%) in cases of aortic aneurysm while thoracic aneurysm showed comparatively poor accumulation. High positivity was also demonstrated in deep vein thrombosis. The complimentary role of this method for intracardiac thrombi to echocardiography was noted. The labeling procedure of indium-111 oxine was fairly easy to perform and the activity of labeled platelets was sustained enough to yield good results. In one case scintigraphy was performed successfully after 19 hours of angiography when a hot area of labeled platelets was seen at the puncture site. This method was therefore varified to be a sensitive and reliable method in the assessment of thrombus activity, and as it demonstrates the activity, its helpfulness in the conservative treatment of these disorders is warranted. |
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| Practice | Clinical medicine |
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| Keywords | 111In-oxine, Platelet, Aortic aneurysm, Thrombosis, Platelet function |
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