Japanese
Title99mTc-DMSAシンチグラフィによる経皮的腎結石破砕術の腎機能に及ぼす影響の評価
Subtitle原著
Authors桜井正樹*, 日置琢一*, 北野外紀雄**, 中川毅***, 山口信夫***, 川村寿一*
Authors(kana)
Organization*三重大学医学部泌尿器科, **中央放射線部, ***放射線科
Journal核医学
Volume25
Number11
Page1215-1220
Year/Month1988/11
Article原著
Publisher日本核医学会
Abstract「要旨」 経皮的腎結石破砕術(Percutaneous Nephrostolithotripsy:PNL)を施行した43例に対し, 99mTc-DMSAシンチグラフィをPNL前後で行い, PNLの腎に及ぼす影響を検討した. シンチグラム後面像では, 15例に腎瘻造設部を中心とした99mTc-DMSAの集積の低下が認められた. しかしcold areaとして認められるような大きな変化は, 2例に認められるのみであった. SPECT像では5例に変化を認めた. 腎機能の変化は, PNL施行側腎の対側の腎に対する摂取率の比を求め, この値の変化で検討した. その結果, PNLにより患側の腎は4〜8週後では95.8±8.7%と有意に低下した. 12例は約1年後にも再検討したが, 全例4〜8週後の値より改善していた. PNLが腎に及ぼす影響はあまり大きくなく, 臨床的には問題ないと思われる. またPNLの腎に及ぼす影響を検討する上で, 99mTc-DMSAシンチグラフィはきわめて有効であった.
Practice臨床医学:一般
KeywordsPNL(Percutaneous Nephrostolithotripsy), 99mTc-DMSA scintigraphy, Renal function
English
TitleRenal Function Assessed by 99mTc-DMSA Scintigraphy Before and After Percutaneous Nephrostolithotripsy (PNL)
Subtitle
AuthorsMasaki SAKURAI*, Takuichi HIOKI*, Tokio KITANO**, Tsuyoshi NAKAGAWA***, Nobuo YAMAGUCHI***, Juich KAWAMURA*
Authors(kana)
Organization*Department of Urology, **Central Clinical Division of Radiology, ***Department of Radiology, Mie University of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume25
Number11
Page1215-1220
Year/Month1988/11
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] 99mTc-DMSA scintigraphy was carried out in 43 patients with unilateral renal stones before and after PNL. This study was repeated about one year after PNL in 12 patients. DMSA renal uptake was calculated two hours after injection of 99mTc-DMSA. The study was performed using the dual type gamma camera. The renal function was assessed by the formula:99mTc-DMSA renal uptake of the operated side/99mTc-DMSA renal uptake of the contralateral side. The change (ratio before/after PNL) ×100 was regarded as the percent change of renal function. Local abnormalities in the 99mTc-DMSA renal scintigram after PNL were observed in 15 patients. The renal function decreased significantly to 95.8+-8.7% from the base line 4-8 weeks after PNL. The renal function improved significantly to 98.6+-14.7% from 92.1+-11.9% in 12 patients about one year after PNL. It is concluded that although the renal function slightly decreased 4-8 weeks after PNL, it is expected to improve within 1 year after PNL, 99mTc-DMSA scintigraphy is a useful adjunct to evaluate the renal function before and after PNL.
PracticeClinical medicine
KeywordsPNL(Percutaneous Nephrostolithotripsy), 99mTc-DMSA scintigraphy, Renal function

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