Japanese
Titleタリウム-201冠動脈直接注入による心筋シンチグラム像の検討
Subtitle原著
Authors杉原洋樹*, 稲垣末次*, 窪田靖志*, 中川達哉*, 片平敏雄*, 東秋弘*, 大森斎*, 立川弘孝*, 白山武司*, 辰巳哲也*, 古川啓三*, 井上大介*, 足立晴彦*, 朝山純*, 勝目紘*, 中川雅夫*
Authors(kana)
Organization*京都府立医科大学第二内科
Journal核医学
Volume25
Number10
Page1095-1102
Year/Month1988/10
Article原著
Publisher日本核医学会
Abstract「要旨」冠動脈内に直接タリウム-201を注入することにより得られる心筋シンチグラム像を検討した. 心臓カテーテル検査終了直前に左または右冠動脈あるいは両冠動脈内にタリウム-201を約1mCi注入し, 心筋灌流像を得た. その結果, 静脈内投与よりも少ない投与量にてバックグラウンドの少ない明瞭な心筋灌流像が得られた. 左右どちらか一方の冠動脈内のみ注入の場合は, それぞれの灌流域に相当した心筋灌流像を呈し, また側副血行路の存在下ではそれを介する灌流状態をもよく反映する像が得られた. さらに, 右冠動脈内へのタリウム-201投与時には左室のみならず右室も良好に描出されたが, 不整脈源性右室異形成の1例では右室心尖部に灌流欠損像を呈し, これは電気生理学的検査による心室性頻拍の発生部位と一致した. 本法は冠動脈造影による冠動脈の解剖学的所見と冠灌流状態の関係, 側副血行路の心筋灌流への寄与の程度, またバイパスグラフトの灌流域を明瞭にする有用な方法であり, さらに右室病変の把握にも役立つと考えられた.
Practice臨床医学:一般
KeywordsThallium-201 scintigraphy, Coronary blood flow, Coronary arteriography.
English
TitleMyocardial Imaging by Direct Injection of Thallium-201 into Coronary Artery
Subtitle
AuthorsHiroki SUGIHARA, Suetsugu INAGAKI, Yasushi KUBOTA, Tatsuya NAKAGAWA, Toshio KATAHIRA, Akihiro AZUMA, Itsuki OMORI, Hirotaka TATSUKAWA, Tetsuya TATSUMI, Takeshi SHIRAYAMA, Daisuke INOUE, Keizou FURUKAWA, Jun ASAYAMA, Haruhiko ADACHI, Hiroshi KATSUME, Masao NAKAGAWA
Authors(kana)
OrganizationSecond Department of Internal Medicine, Kyoto Prefectural University of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume25
Number10
Page1095-1102
Year/Month1988/10
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractMyocardial perfusion images were evaluated by direct injection of Thallium (Tl)-201 into coronary artery. Approximately 0.5-1 mCi of Tl-201 were instilled into the right coronary artery and/or the left coronary artery after coronary arteriography. Three images were obtained in the anterior, left anterior oblique and left lateral projections. Myocardial perfusion images of single photon emission computed tomography were also acquired in some patients. An image of supreme quality could be obtained in spite of small dose of Tl-201 since there was a lack of interference from background activity. Myocardial perfusion images corresponded to areas which were supplied by left or right coronary artery respectively. And the regional myocardial blood flow distribution of a coronary artery bypass graft could be revealed by instilling Tl-201 into the graft. Further, contribution of collateral channels to myocardial perfusion was showed. Not only left ventricle but also right ventricle was clearly visualized by injection of Tl-201 into right coronary artery. But in a case with arrhythmogenic right ventricular dysplasia, there was an area of decreased tracer uptake in the apex of the right ventricle which was identified as the site of dysplasia by electrophysiologic study. We conclude that direct injection of Tl-201 into coronary artery is an useful method to clarify the correlation between coronary anatomical findings and coronary perfusion and contribution of collaterals to myocardial perfusion, and also to detect the right ventricular myopathic site.
PracticeClinical medicine
KeywordsThallium-201 scintigraphy, Coronary blood flow, Coronary arteriography.

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