| Japanese |
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| Title | 運動負荷Tl-201心筋SPECT像から求めた梗塞領域再分布図による心筋viabilityの定量評価 |
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| Subtitle | 原著 |
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| Authors | 堰合恭弘* |
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| Organization | *弘前大学医学部第二内科 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 8 |
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| Page | 735-742 |
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| Year/Month | 1988/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」健常者10例, 心筋梗塞20例の計30例を対象として運動負荷Tl-201心筋シンチを施行し, 心筋梗塞患者のSPECT像から梗塞領域再分布図を作製して心筋viabilityの定量評価を試みた. 作製した梗塞領域再分布図では左室心筋は再分布のない梗塞巣, 再分布がある梗塞領域, 梗塞周辺の再分布領域の三つの領域に分けて表示され, 再分布領域は梗塞巣を取り囲むように存在した. また, 梗塞領域再分布図から梗塞量の定量指標として求めたdefect score, % defect, ならびに再分布の定量指標として得た再分布比(RR)や再分布指数(RI)はplanar像の視覚的判定結果とほぼ一致した. また, defect scoreと% defectは局所壁運動機能を表す% shorteningと逆相関(それぞれr=-0.573; p<0.05, r=-0.536; p<0.05)を示し, RIは% shorteningと良い正相関関係(r=0.669; p<0.01)にあった. それゆえ本研究で考案作製した梗塞領域再分布図は心筋viabilityを反映し, その定量評価に有用と思われた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Infarct-redistribution map, Myocardial viability, Myocardial infarction, Thallium-201 myocardial SPECT. |
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| English |
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| Title | Quantitative Estimation of Viable Myocardium in the Infarcted Zone by Infarct-Redistribution Map from Images of Exercise Thallium - 201 Emission Computed Tomography |
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| Subtitle | - Original Articles - |
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| Authors | Yasuhiro SEKIAI |
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| Organization | The Second Department of Internal Medicine, Hirosaki University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 8 |
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| Page | 735-742 |
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| Year/Month | 1988/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | To evaluate, quantitatively, the viable myocardium in the infarcted zone, we invented the infarct-redistribution map which is produced from images of exercise thallium-201 emission computed tomography performed on 10 healthy subjects and 20 patients with myocardial infarction. The map displayed a left ventricle in which the infarcted area both with and without redistribution, the redistribution area without infarction, and normal perfusion area were shown separated in same screen. In these circumstances, the nonredistribution infarct lesion was found as being surrounded by the redistribution area. Indices of infarct and redistribution extent (defect score, % defect, redistribution ratio (RR) and redistribution index (RI)), were induced from the map and were used for quantitative analysis of the redistribution area and as the basis for comparative discussion regarding regional wall motion of the left ventricle. The quantitative indices of defect score, % defect, RR and RI were consistent with the visual assessment of planar images in detecting the extent of redistribution. Furthermore, defect score and % defect had an inverted linear relationship with % shortening (r=-0.573; p<0.05, r=-0.536; p<0.05, respectively), and RI had a good linear relationship with % shortening (r=0.669; p<0.01). We conclude that the infarct-redistribution map accurately reflects the myocardial viability and therefore may be useful for quantitative estimation of viable myocardium in the infarcted zone. |
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| Practice | Clinical medicine |
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| Keywords | Infarct-redistribution map, Myocardial viability, Myocardial infarction, Thallium-201 myocardial SPECT. |
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