| Japanese |
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| Title | I-123IMPとTc-99m HMPAOが異常集積を示した多形性神経膠芽細胞腫の1例 |
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| Subtitle | 症例報告 |
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| Authors | 前田尚利*, 古林秀則**, 林實**, 石井靖* |
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| Authors(kana) | |
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| Organization | *福井医科大学放射線科, **脳神経外科 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 7 |
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| Page | 655-658 |
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| Year/Month | 1988/7 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 I-123IMPおよびTc-99m HMPAOはレセプタや血液脳関門欠如などの理由により, 通常脳腫瘍には集積しないと考えられているが, 今回われわれはこれらの放射性薬品が多形性神経膠芽細胞腫に集積した症例を経験したので報告する. 1週間の間隔をおいてSPECTを用いて脳血流シンチグラフィを行った. X線CTおよび脳外科手術にて確認された腫瘍の部位に集積増加を認めた. 断層像の重ね合わせ方による比較では, Tc-99m HMPAOがI-123IMPよりも相対的に強い集積があり, 本症例においては従来よりいわれているものとは異なる集積機序が示唆された. |
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| Practice | 臨床医学：一般 |
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| Keywords | I-123IMP, Tc-99m HMPAO, Brain scintigraphy, Glioblastoma multiforme. |
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| English |
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| Title | Unusual Accumulation of I-123 IMP and Tc-99m HMPAO in Glioblastoma Multiforme |
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| Subtitle | Case Report |
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| Authors | Hisatoshi MAEDA*, Hidenori KOBAYASHI**, Minoru HAYASHI**, Yasushi ISHII* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Fukui Medical School, **Department of Neurosurgery, Fukui Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 7 |
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| Page | 655-658 |
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| Year/Month | 1988/7 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Brain neoplasms are believed not to accumulate I-123IMP or Tc-99m HMPAO, because these tumors usually lack receptors or other accumulation mechanisms yet undetermined. A 62-year-old male patient with a brain tumor (glioblastoma multiforme) was studied with these radiopharmaceuticals. The two radiopharmaceuticals exhibited the increased uptakes in both the tumor and the adjacent edematous tissue which showed low density by the conventional X-ray CT. Transaxial images of the two radiopharmaceuticals were obtained with SPECT and the accumulations were compared with a pixel-by-pixel basis. Tc-99m HMPAO accumulated more intensely than I-123 IMP in the tumor, however, the diaschisis on the contralateral side had the same degree of accumulation. |
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| Practice | Clinical medicine |
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| Keywords | I-123IMP, Tc-99m HMPAO, Brain scintigraphy, Glioblastoma multiforme. |
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