| Japanese |
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| Title | 運動負荷Tl-201心筋SPECTによる遅延再分布の検討 |
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| Subtitle | 原著 |
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| Authors | 武藤敏徳* |
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| Authors(kana) | |
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| Organization | *東邦大学医学部第一内科 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 7 |
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| Page | 639-646 |
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| Year/Month | 1988/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」運動負荷タリウム心筋シンチグラフィで, 一部の症例で再分布が著しく遅延することがある. このため, 虚血性心疾患57例に対して運動負荷タリウムSPECTを施行し, 通常の方法に加え23時間後にも遅延スキャンを行い, 遅延再分布について定量解析を行うとともにその臨床的意義について検討した. 57例中22例 (38.6%) に遅延再分布が認められた. 遅延再分布群でのextent scoreおよびseverity scoreは, 4時間と23時間でそれぞれ0.43±0.21から0.29±0.19, 57.3±46.4から32.4±30.4と有意 (P<0.05) な減少が見られた. 遅延再分布群のwashout rateは, 遅延再分布領域だけでなく, 左室全体でも低値であった. また, 断層心エコー図では, 遅延再分布領域での局所壁運動に収縮が認められた. 以上のことより, 遅延スキャンはwashout rateの低い症例での心筋のviabilityの評価に有用と思われた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Exercise thallium-201 myocardial scintigraphy, Single photon emission computed tomography, Redistribution, Coronary artery disease. |
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| English |
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| Title | Assessment of Thallium-201 Late Redistribution in Exercise Myocardial SPECT |
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| Subtitle | Original Articles |
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| Authors | Toshinori MUTO |
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| Authors(kana) | |
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| Organization | The First Department of Internal Medicine, Toho University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 7 |
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| Page | 639-646 |
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| Year/Month | 1988/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Redistribution of Thallium-201 following exercise stress may continue to occur for more than 2 to 6 hours in some patients, and possibility exists to underestimate the viability of myocardium with delayed scan at those times. 57 patients with coronary artery disease underwent multistage treadmill exercise. Thallium-201 myocardial SPECT were obtained immediately after exercise, 4 hours and 23 hours later. Quantitative analysis was performed with circumferential profiles of continuous 9 short axial images of left ventricle. With visual interpretation, 22 of 57 patients (38.6%) showed late redistribution. In the group with late redistribution, extent score was 0.43+-0.21 at 4 hours and 0.29+-0.19 at 23 hours. Severity score was 57.3+-46.4 at 4 hours and 32.4+-30.4 at 23 hours. These differences were statistically significant (p<0.05) . The washout rate in patients with late redistribution was significantly lower than that in patients without late redistribution not only at the area of late redistribution but also at the remainder areas including normal area. An assessment of regional wall motion revealed that most of the myocardial segments with late redistribution preserved contraction. From these observations, it is considered that late scans are useful in order to estimate myocardial viability especially in cases which shows slow tracer washout. |
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| Practice | Clinical medicine |
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| Keywords | Exercise thallium-201 myocardial scintigraphy, Single photon emission computed tomography, Redistribution, Coronary artery disease. |
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