| Japanese |
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| Title | 123I-IMP SPECTによるてんかん症例の検討 |
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| Subtitle | 原著 |
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| Authors | 南部敏和*, 伊藤和夫**, 角哲雄***, 古舘正従**, 入江五朗* |
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| Authors(kana) | |
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| Organization | *北海道大学医学部放射線科, **核医学科, ***精神神経科 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 6 |
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| Page | 525-531 |
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| Year/Month | 1988/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 成人部分てんかん患者22回の検査 (21例) において, 病巣部の局在診断に関して123I-IMP SPECT像と脳波 (EEG) を比較検討した. 123I-IMP SPECT像では肉眼的に集積異常がみられたのは13回であり, そのうち7回は脳波でのてんかん性異常波の中心部位と一致していた. 脳波をもとに, カウント比による定量解析を試みたが, 脳波およびSPECT所見の特異性, 正確性, 相関に問題があるためか, 統計学的有意差は認められなかった. ただし, 発作頻度が高い症例ほど集積異常がみられる傾向があり, 123I-IMP SPECTは, 今後てんかんの診断と治療に応用が広がっていくことが期待される. |
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| Practice | 臨床医学：一般 |
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| Keywords | Single photon emission CT, Epilepsy, N-Isopropyl[I-123]-p-Iodoamphetamine |
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| English |
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| Title | Evaluation of SPECT with N-Isopropyl[I-123]-p-Iodoamphetamine (IMP) in Epileptic Patients |
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| Subtitle | Original Articles |
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| Authors | Toshikazu NAMBU*, Kazuo ITOH**, Tetsuo SUMI***, Masayori FURUDATE**, Goro IRIE* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Nuclear Medicine, ***Department of Psychiatry, Hokkaido University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 6 |
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| Page | 525-531 |
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| Year/Month | 1988/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Brain SPECT scintigrams with N-Isopropyl[I-123]-p-Iodoamphetamine (IMP) were reviewed and compared with the EEG findings in 21 epileptic patients (22 SPECT images) with normal CT. Thirteen of 22 SPECT images showed abnormal low uptake and 7 of them corresponded to the EEG focus. In order to obtain the quantitative analysis, the count ratio of the focus side to the opposite I-123 content in fixed ROI was measured for each case, but no statistically significant correlation for the frequency or the duration of epilepsy was found. EEG is not considered to be favorite standard for localizing epileptic foci, especially in deep cerebral region, and that may be one of the main reason for the incomplete correlation. In the qualitative study, however, the cases with frequent epileptic attack were more likely to show abnormal findings. I-123 IMP SPECT can now be considered as having a significant clinical role for the diagnosis and management of patients with epilepsy. |
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| Practice | Clinical medicine |
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| Keywords | Single photon emission CT, Epilepsy, N-Isopropyl[I-123]-p-Iodoamphetamine |
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