| Japanese |
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| Title | 下肢運動障害患者に対するイソプロテレノール負荷Tl心筋SPECTの有用性の検討 |
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| Subtitle | 原著 |
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| Authors | 相澤信行*, 金國鐘*, 原芳邦*, 清水俊夫*, 三井民人**, 川崎愉紀**, 鈴木豊*** |
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| Authors(kana) | |
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| Organization | *茅ケ崎徳洲会病院循環器内科, **放射線科, ***東海大学医学部放射線科I |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 5 |
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| Page | 423-430 |
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| Year/Month | 1988/5 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」下肢運動障害のあるためにTreadmill試験が不可能な患者27名に対してイソプロテレノール負荷タリウム心筋SPECTを施行した, イソプロテレノール0.3-1.0 μg/kgまでを持続静注し, 胸部症状出現, 心電図変化等のときには静注を中止し塩化タリウム2 mCiを静注, 3分後よりSPECT撮影を開始した. 3時間後に再分布像を撮影した. 全例冠状動脈造影を施行し, 所見を対比した. 冠状動脈造影上の狭窄または閉塞の有無は心筋シンチグラフィー上の永続的欠損または再分布陽性の有無と一致した. その灌流域にviableな心筋を伴った冠状動脈の狭窄を心筋シンチグラフィーから予測するとSensitivity 87%, Specificity 100%となった. 重大な合併症はなかった. 以上より, イソプロテレノール負荷タリウム心筋SPECTは, 安全, かつ簡便で下肢運動障害患者の虚血性心疾患の検出に有用であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Isoproterenol, Thallium myocardial scintigraphy, Single photon emission computed tomography (SPECT) , Lower extremity impairment |
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| English |
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| Title | Thallium-201 Myocardial Single Photon Emission Computed Tomography after Isoproterenol Infusion in Diagnosing Ischemia Heart Disease |
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| Subtitle | Original Articles |
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| Authors | Nobuyuki AIZAWA*, Kunikane KIM*, Yoshikuni HARA*, Toshio SHIMIZU*, Tamito MITSUI**, Yuki YAMAZAKI**, Yutaka SUZUKI*** |
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| Authors(kana) | |
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| Organization | *Department of Cardiology, **Department of Radiology, Chigasaki Tokushuukai Medical Center, ***Department of Radiology I, Tokai University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 5 |
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| Page | 423-430 |
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| Year/Month | 1988/5 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Patients with obstructive atherosclerotic diseases of the peripheral arteries are often unable to undergo a standard Treadmill test for evaluation of concomitant coronary artery diseases. To establish an alternative method of testing, 27 patients had intravenous infusion of isoproterenol, up to 1.0 μg/kg, in conjugation with myocardial thallium-201 single photon emission computed tomography (SPECT) . All underwent coronary angiography. Thallium-201 myocardial SPECT after isoproterenol infusion was found to have 100% sensitivity and 100% specificity for detecting coronary artery diseases (stenotic or occluded coronary arteries with or without myocardial infarction) and 87% sensitivity and 100% specificity for detecting stenotic coronary arteries with viable regional myocardium. No major complication was experienced during and after this study. It is concluded that serial thallium-201 myocardial SPECT after isoproterenol infusion is safe, reliable and useful for detecting coronary artery disease when standard exercise test is not feasible. |
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| Practice | Clinical medicine |
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| Keywords | Isoproterenol, Thallium myocardial scintigraphy, Single photon emission computed tomography (SPECT) , Lower extremity impairment. |
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