| Japanese |
|---|
| Title | 虚血心筋におけるフルオロデオキシグルコースの集積 - (第3報) 冠動脈バイパス術前後での検討 - |
|---|
| Subtitle | 原著 |
|---|
| Authors | 玉木長良*, 米倉義晴*, 山下敬司*, 千田道雄*, 佐治英郎*, 山本和高*, 西澤貞彦*, 平田和男**, 小西裕**, 伴敏彦**, 小西淳二* |
|---|
| Authors(kana) | |
|---|
| Organization | *京都大学医学部放射線核医学科, **心臓血管外科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 25 |
|---|
| Number | 5 |
|---|
| Page | 413-421 |
|---|
| Year/Month | 1988/5 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」虚血性心疾患14例の冠動脈バイパス術前後に13N-アンモニアおよび18FDGを用いたポジトロンCT検査を施行し, 術前に血流低下した領域で18FDG集積の有無より術後の組織血流・壁運動の改善の予測を行った. 術後血流の改善したのは術前の18FDG (+) の64%, 18FDG (-) の31%であった (P<0.05) . 一方壁運動の改善したのは術前18FDG (+) の78%, 18FDG (-) の20%であった (P<0.002) . 術前18FDG (+) であった14区域のうち, 術後18FDG集積の消失したのは7区域 (50%) であった. この領域の大部分は血流も壁運動も改善した (おのおの86%, 100%) のに対し, 18FDG集積の残存した領域ではあまり改善が期待できなかった (おのおの43%, 60%) . 以上より術前の18FDG集積の有無から術後の組織血流と壁運動の改善の予測が可能と考えられた. また18FDGの集積はバイパス術後でも必ずしも消失せず, その推移は心筋障害の程度の経時的変化を反映する点で有用と考えられた. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Positron emission tomography, Coronary bypass surgery, 18F-fluorodeoxyglucose, Wall motion, Myocardial ischemia. |
|---|
| English |
|---|
| Title | Accumulation of Fluorodeoxyglucose in Ischemic Myocardium : III. Assessment of the Effects of Coronary Bypass Surgery |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Nagara TAMAKI*, Yoshiharu YONEKURA*, Keiji YAMASHITA*, Michio SENDA*, Hideo SAJI*, Kazutaka YAMAMOTO*, Sadahiko NISHIZAWA*, Kazuo HIRATA**, Yutaka KONISHI**, Toshihiko BAN**, Junji KONISHI* |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology and Nuclear Medicine, **Department of Cardiovascular Surgery, Kyoto University School of Medicine |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 25 |
|---|
| Number | 5 |
|---|
| Page | 413-421 |
|---|
| Year/Month | 1988/5 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] Positron emission tomography using 13N-ammonia and 18F-fluorodeoxyglucose (18FDG) was performed before and after coronary bypass surgery in 14 patients with coronary artery disease. The predictive values of preoperative uptake of 18FDG in the hypoperfused segments were assessed for postoperative improvement in regional perfusion and wall motion. An improvement in regional perfusion was observed more often in the segments with an increase in 18FDG uptake (64%) than those with no increase in its uptake (31%) (p<0.05) . An improvement in regional wall motion was observed more often in those with an increased 18FDG uptake (78%) than those with no increased uptake (20%) (p<0.002) . Furthermore, among 14 segments with an increased 18FDG uptake preoperatively, 7 segments (50%) showed a decrease in uptake postoperatively. These segments tend to improve in regional perfusion (86%) and wall motion (100%) , as compared to those with similar 18FDG uptake (43% and 60%, respectively) postoperatively. These data suggest that preoperative uptake of 18FDG may be valuable for predicting improvement in regional perfusion and wall motion by coronary bypass surgery. An increased 18FDG uptake may often remain after the surgery, which is considered to reflect tissue damage in the ischemic myocardium. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Positron emission tomography, Coronary bypass surgery, 18F-fluorodeoxyglucose, Wall motion, Myocardial ischemia. |
|---|