| Japanese |
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| Title | 急性心筋梗塞における負荷時左室駆出率の変化および罹患冠動脈病変とRI諸指標の相互関係 |
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| Subtitle | 原著 |
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| Authors | 木下栄治* |
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| Authors(kana) | |
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| Organization | *東海大学医学部第一内科 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 4 |
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| Page | 311-321 |
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| Year/Month | 1988/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」急性心筋梗塞 (AMI) で, 左室駆出率 (LVEF) の負荷時の変化や罹患冠動脈病変を, 安静負荷時のRI諸指標より推定し得るか否かを検討した. 対象は, AMI患者61例で, 発症21〜28病日に負荷RI心室造影を施行し, LVEFの変化をΔLVEFとし, 安静時の諸指標と比較検討した. また負荷心筋スキャンから負荷直後・4時間後の心筋灌流指数の差をΔTLPIとした. さらに, 冠状動脈造影より病変部を, 多枝病変群 (MVD) , 一枝病変群 (SVD) に分類し, ΔLVEF, ΔTLPIとの関係を検討した. ΔLVEFと安静時位相解析の標準偏差 (SD) に負の相関を認めた (r=-0.41, P<0.01) . またSDが30以下の例はΔLVEFが有意に増大する傾向にあった (P<0.01) . ΔLVEF, ΔTLPIでは, MVDでΔLVEFが5%以下の例が多く, SVDはΔTLPIの不変例が多く, 感受性はそれぞれ, 80.7%, 81.5%であった. 以上のことから, 負荷時LVEFの変化を安静時のSDから, また罹患冠動脈病変をLVEFやTLPIの変化から類推することが可能であると考えた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium perfusion index, Phase analysis, Peak filling rate, Acute myocardial infarction. |
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| English |
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| Title | The Correlation among the LVEF Response during Exercise, Diseased Coronary Arteries and RI Parameters in Acute Myocardial Infarction |
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| Subtitle | Original Articles |
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| Authors | Eiji KINOSHITA |
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| Authors(kana) | |
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| Organization | Department of Internal Medicine, Tokai University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 4 |
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| Page | 311-321 |
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| Year/Month | 1988/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] This study was carried out to establish correlation between; 1: some parameters of radionuclide ventriculography (RNVG) at rest and change of left ventricular ejection fraction (LVEF) during exercise, 2: the number of diseased coronary arteries and some parameters of RNVG and exercised thallium myocardial scintigraphy (EXTM) . Sixty-one patients were included in this study. All patients submitted RNVG. EXTM and coronary angiography (CAG) were performed in 53 of 61 patients with 7 weeks after the attack of AMI. These 53 patients were divided in 2 groups according to the number of diseased coronary arteries: multi-vessel disease (MVD) and single vessel disease (SVD) . The change of LVEF at rest and exercise (ΔLVEF) had significant correlation with standard deviation of phase analysis (SD) at rest (r=-0.41, p<0.01) . Increased LVEF during exercise was seen in 31 of 37 patients with SD degree below 30 (sensitivity=83.3%) . Twenty-one of 26 MVD patients presented ΔLVEF below 5% (sensitivity=80.7%, p<0.01) . Twenty-two of 27 SVD patients showed the score of ΔTLPI (difference of thallium perfusion index immediately and 4 hours after EX) within 1 (sensitivity=81.5%, p<0.01) . Conclusion: SD at rest was a good parameter to predict the change of LVEF during EX, and both ΔLVEF and ΔTLPI had significant correlation with the number of diseased coronary arteries. |
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| Practice | Clinical medicine |
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| Keywords | Thallium perfusion index, Phase analysis, Peak filling rate, Acute myocardial infarction. |
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