| Japanese |
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| Title | 肺血流シンチグラフィによる肺換気運動イメージの作成 |
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| Subtitle | 原著 |
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| Authors | 藤井忠重*, 金井久容**, 平山二郎*, 半田健次郎*, 草間昌三*, 矢野今朝人***, 平野浩志*** |
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| Authors(kana) | |
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| Organization | *信州大学医学部第一内科, **丸の内病院内科, ***信州大学医学部附属病院中央放射線部 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 4 |
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| Page | 301-310 |
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| Year/Month | 1988/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」肺・胸郭系の換気による動きを解析する目的で, シンチカメラ-ミニコンピュータシステムを用い, 99mTc-MAAの肺血流シンチグラフィを応用した肺換気運動イメージを考案した. 最大吸気位 (I) および最大呼気位 (E) の肺血流シンチグラムから, 99mTc-MAA粒子を肺局所の指標とし, 換気に伴うMAA粒子の分布密度の変化を放射能の変化率 (E-I) /Iとして算出し, その機能像を作成した. (E-I) /Iの (+) 成分の画像は肺内の動きを示し, 局所換気量とほぼ対応する分布パターンを示し, その両肺の総和は肺活量とr=0.83の相関を認めた. (E-I) /Iの (-) 成分の画像は肺辺縁, 横隔膜の動きを描出し, これらの異常が検出できた. 本法は換気による肺・胸郭系の動きを多方向から評価でき, 局所肺とともに1側肺ないし両側肺当たりの動きを定量でき有用である. |
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| Practice | 臨床医学：一般 |
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| Keywords | Perfusion lung scintigram, Lung motion, Functional image, Regional ventilation, Regional pulmonary function. |
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| English |
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| Title | Imaging of Ventilatory Lung Motion Using Perfusion Lung Scintigrams |
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| Subtitle | Original Articles |
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| Authors | Tadashige FUJII*, Hisakata KANAI*, Jiro HIRAYAMA*, Kenjiro HANDA*, Shozo KUSAMA*, Kesato YANO**, Hiroshi HIRANO** |
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| Authors(kana) | |
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| Organization | *The First Department of Internal Medicine, **Division of Radiology, Shinshu University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 4 |
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| Page | 301-310 |
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| Year/Month | 1988/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Applying perfusion lung scintigrams, functional images representing the motion of the regional pulmonary areas and lung edges during ventilation were obtained in patients with various respiratory diseases. Perfusion lung images at maximal inspiration (I) and expiration (E) were recorded for 7-20 seconds and stored after the intravenous injection of 99mTc-macroaggregated albumin (6-10 mCi) , using a scintillation camera with a small digital computer. Changes of the radioactivity during ventilation in each pixel were calculated using an expression as (E-I) /I, and the functional image of (E-I) /I was obtained. The image of (E-I) /I consisted of positive and negative components. The positive component of (E-I) /I visualized the motion of the regional pulmonary areas during ventilation, that nearly corresponded with regional ventilation on videodensigram and inhalation image of 81mKr. The negative component of (E-I) /I visualized the motion of the lung edges including the diaphragm during ventilation. The sum total of positive (E-I) /I in the both lungs of the anterior image was correlated with that of the posterior image (n=30, r=0.81) and vital capacity (n=30, r=0.83) . The sum total of positive (E-I) /I in the right lung of the anterior image was correlated with that of the right lateral image, but there was no correlation between the sum total of positive (E-I) /I in the left lung of the anterior image and left lateral image. This technique seems to be useful for the estimation of the regional pulmonary ventilation and motion of the lung edges. |
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| Practice | Clinical medicine |
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| Keywords | Perfusion lung scintigram, Lung motion, Functional image, Regional ventilation, Regional pulmonary function. |
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