Japanese
TitleThallium-201心筋single photon emission computed tomographyの定量性の検討 - ファントムを用いて -
Subtitle原著
Authors大嶽達*, 渡辺俊明*, 小坂昇*, 百瀬敏光*, 西川潤一*, 飯尾正宏*
Authors(kana)
Organization*東京大学医学部放射線科
Journal核医学
Volume25
Number3
Page255-264
Year/Month1988/3
Article原著
Publisher日本核医学会
Abstract「要旨」われわれは人体に近い条件の胸部ファントム, および部位により壁厚や壁内Tl-201濃度を変えた心筋ファントムを用い, 回転型ガンマカメラによるSPECT画像を得て, 画像上の心筋各部位のカウントと壁厚や壁内Tl-201濃度との関係を検討した. その結果360度スキャン, 180度スキャンのいずれでも1cmを100%として壁厚を変化させた場合と1cmの壁厚でTl-201濃度を変えた場合, 壁厚も濃度もSPECT画像上の心筋壁のカウントとほぼ比例した. しかも100%, 75%, 50%, 25%, 0%の5段階を十分識別可能であった. しかし, 180度スキャンでは壁上部が壁下部より10から15%カウントが低下し, 後下壁も前壁より10%程度カウントが低下するなど360度スキャンよりも部位によるカウントの差が大きかった. このような誤差を考慮すれば, Tl心筋SPECTの欠損の程度から, 梗塞巣の残存心筋量や一過性虚血巣の虚血の程度を評価可能と考えた.
Practice臨床医学:一般
KeywordsTl-201 myocardial scan, SPECT, Phantom study, 180°scan, 360°scan.
English
TitlePhantom Study of Thallium-201 Myocardial Single Photon Emission Computed Tomography for Evaluating its Ability to Quantify Residual Myocardium in Infarct Area
SubtitleOriginal Articles
AuthorsTohru OHTAKE, Toshiaki WATANABE, Noboru KOSAKA, Toshimitsu MOMOSE, Junichi NISHIKAWA, Masahiro Iio
Authors(kana)
OrganizationDepartment of Radiology, Faculty of Medicine, University of Tokyo
JournalThe Japanese Journal of nuclear medicine
Volume25
Number3
Page255-264
Year/Month1988/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] We studied the relationship between the count of myocardial wall in single photon emission computed tomography (SPECT) image and the thickness of wall or the concentration of Thallium-201 (Tl) in wall. For this purpose, we used phantom of thorax and myocardium. Thoracic phantom consists of mediastinum filled with low concentrated Tl solution and lung filled with wooden tip. Myocardial phantom consists of eight parts (upper and lower parts of anterior wall, septum, posteroinferior wall and lateral wall). In one phantom we changed the thickness of wall (10 mm, 7.5 mm, 5 mm, 2.5 mm, 0 mm) and in another phantom we changed the Tl concentration (100%, 75%, 50%, 25%, 0%). In our results, the thickness and the concentration correlated well with the count and five grades (100%, 75%, 50%, 25%, 0%) were well separated though it was said that SPECT is inaccurate in quantification. But in 180° half scan, the count of upper part was 10-15% lower than that of lower part and the count of posteroinferior wall was about 10% lower than that of anterior wall. We have to take it into account in quantification. In conclusion, using Tl-201 myocardial SPECT residual myocardium in infarct area can be evaluated from the severity of defect, and from that the severity of ischernia can be evaluated.
PracticeClinical medicine
KeywordsTl-201 myocardial scan, SPECT, Phantom study, 180°scan, 360°scan.

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