| Japanese |
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| Title | 虚血性脳血管障害に対する123I-IMPを用いたSPECT - delayed imageの検討 - |
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| Subtitle | 原著 |
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| Authors | 村田純一*, 金子貞男*, 今井知博* |
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| Organization | *岩見沢市立総合病院脳神経外科 |
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| Journal | 核医学 |
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| Volume | 25 |
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| Number | 2 |
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| Page | 117-124 |
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| Year/Month | 1988/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」虚血性脳血管障害患者35例に対して123I-IMPによるSPECT earlyおよびdelayed imageを全例に行い, CTおよび臨床症状との対比において, delayed imageの意義について検討した. この結果, early imageで低血流部位があり, これがCTで梗塞である症例群では, delayed imageでも無〜低集積を示し, 臨床症状はcompleted strokeである場合が多く, 一方, early imageで低血流部位があってもCTで正常である症例群では, delayed imageでほぼ正常集積を示し, 臨床的にも無症状またはTIAあるいはRINDである場合が多かった, これより, delayed imageが組織の可逆性を反映している可能性があると考えられた. ただし亜急性期には, 梗塞部がearly imageで低集積であっても, delayed imageで高集積を示すことがあり, その機序は不明であるが, 画像読影の際に注意を要すると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-IMP, SPECT, Cerebral blood flow, Computed tomography, Cerebrovascular disease. |
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| English |
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| Title | 123I-IMP SPECT in Ischemic Cerebrovascular Disorders - Evaluation of Delayed Image - |
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| Subtitle | Original Articles |
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| Authors | Junichi MURATA, Sadao KANEKO, Tomohiro IMAI |
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| Authors(kana) | |
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| Organization | Department of Neurosurgery, Iwamizawa Municipal General Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 25 |
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| Number | 2 |
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| Page | 117-124 |
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| Year/Month | 1988/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Brain perfusion studies were performed on 35 patients with ischemic cerebrovascular disorders by single photon emission computed tomography (SPECT) using N-isopropyl-p-[123I] iodoamphetamine (IMP). Both early [15-65 min postinjection (p.i.)] and late [5-6 hr p.i.] scan were performed in each case. In comparison with X-ray computed tomographic (CT) findings and clinical symptoms, we evaluated the significance of the late scan and found some correlations between them. Infarcted areas on CT showed low IMP uptake on the late scan, but not-infarcted areas which showed decreased initial uptake revealed nearly normal uptake on the late scan. Therefore, it is likely that the late scan reflects the reversibility or function of the brain tissue. But in subacute phase, some cases of cerebral infarction showed high IMP uptake on the late scan, even though their initial uptake was low. Though we can't explain the mechanism of this phenomenon, we must be aware of it when we read IMP brain scans. |
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| Practice | Clinical medicine |
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| Keywords | 123I-IMP, SPECT, Cerebral blood flow, Computed tomography, Cerebrovascular disease. |
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