| Japanese |
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| Title | 位相解析による運動負荷時壁運動異常の評価とその限界 |
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| Subtitle | 原著 |
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| Authors | 梅澤滋男*, 藤原秀臣**, 平井正幸**, 関延孝**, 廣江道昭***, 谷口興一**** |
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| Authors(kana) | |
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| Organization | *横須賀共済病院内科, **土浦協同病院内科, RI室, ***東京女子医科大学放射線科核医学部, ****東京医科歯科大学第二内科 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 12 |
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| Page | 1757-1764 |
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| Year/Month | 1987/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」心拍同期心プール像位相解析が運動負荷時の壁動態異常の検出に有用であるかを検討する目的で, 狭心症12例, 心筋梗塞+狭心症12例, 陳旧性前壁梗塞17例, 正常10例を対象としTc-99m運動負荷心プールシンチを施行した. 左室位相角の標準偏差(SD)は駆出率と-0.7〜-0.8の負の相関を示し, この相関関係は心拍数の増大により影響されなかった. 負荷に伴うSD値の変化を検討すると狭心症例ではSD値はcontrol時有意に増大したが, ISDN, nifedipine, propranolol投与後にはこの増大は抑制された. これに対し, 前壁梗塞例では安静時のSD値は壁動態異常を反映すると考えられるものの, 負荷時の反応には一定の傾向は認められなかった. 以上より, 狭心症例においては負荷に伴うSD値の増大は虚血に伴う心機能の低下ならびに不均等収縮を示す指標となりうるが, 梗塞例においては負荷時のSD値の変動には問題があり今後の検討が必要と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Radionuclide angiography, Ergometer exercise, Phase analysis, Ischemic heart disease. |
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| English |
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| Title | The Usefulness of Phase Analysis of Gated Radionuclide Angiography in the Patients with Ischemic Heart Disease |
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| Subtitle | - Original Articles - |
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| Authors | Shigeo UMEZAWA*, Hideomi FUJIWARA**, Masayuki HIRAI**, Nobutaka SEKI**, Michiaki HIROE***, Koichi TANIGUCHI**** |
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| Authors(kana) | |
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| Organization | *Yokosuka Kyosai Hospital, **Tsuchiura Kyodo Hospital, ***The Division of Nuclear Medicine, Tokyo Women's Medical College, ****The Second Department of Medicine, Tokyo Medical and Dental University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 12 |
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| Page | 1757-1764 |
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| Year/Month | 1987/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | Quantitative evaluation of ventricular contraction abnormality at rest and during exercise was attempted using phase analysis of RBC-Tc-99m radionuclide angiography (RNA). We performed RNA on 51 patients (normal case: 10, angina pectoris: 12, angina pectoris with old myocardial infarction: 12, anterior old myocardial infarction: 17). Standard deviation (SD) of the phase histograms distributed within the left ventricle was calculated. The changes of left ventricular ejection fraction (EF) and magnitude of ST deviation on exercise were also evaluated. In 24 cases with angina pectoris, the SD significantly increased on exercise, while EF decreased with significant ST depression. This increase of the SD on exercise was abolished after administration of ISDN, nifedipine and propranolol. In contrast to this, the SD of the cases with old myocardial infarction variously changed on exercise. These findings indicate that the SD is useful for the assessment of cardiac function and regional wall motion abnormality induced by exercise, although in old myocardial infarction, it is to be determined what those SD changes mean. |
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| Practice | Clinical medicine |
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| Keywords | Radionuclide angiography, Ergometer exercise, Phase analysis, Ischemic heart disease. |
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