| Japanese |
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| Title | 急性心筋梗塞症における心臓核医学指標と心臓予後との関連性 |
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| Subtitle | 原著 |
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| Authors | 鈴木晃夫*, 佐藤昭彦*, 松島英夫*, 林博史*, 外畑巌**, 渡辺俊也***, 板津英孝*** |
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| Authors(kana) | |
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| Organization | *名古屋大学医学部第一内科, **藤田学園保健衛生大学内科, ***国立名古屋病院内科 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 11 |
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| Page | 1607-1616 |
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| Year/Month | 1987/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」急性心筋梗塞 (AMI) 患者76名を対象に, 入院中の心臓核医学検査より重症度指標として, Tc-99mピロリン酸心筋シンチグラムから梗塞面積, RI心血管造影から左室駆出分画 (LVEF) , Tl-201心筋シンチグラムからTl欠損スコアを算出した. これら3指標と発症後1年以内の心事象 (心臓死, 心不全, 梗塞後狭心症および梗塞再発) との関連性を検討した. さらに心臓死あるいは心不全発症例をhigh risk群として一次判別関数を用いて他群との判別閾値を算出し, 長期予後との関係を検討した. 梗塞面積41cm2以上, LVEF42%以下あるいはTl欠損スコア5以上の基準は梗塞発症後の心臓死および心不全発症群の同定に有用であり, 平均2年7か月の観察期間における長期生存率とも関連性を示した. また, 上記指標はmaxCKと有意な相関を示し梗塞量と密接に関連する指標と考えられた. 以上の成績より, AMI早期の心臓核医学指標は心臓予後の推定に有用であると結論された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Acute myocardial infarction, Radionuclide parameters, Cardiac events, Late prognosis. |
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| English |
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| Title | Prognostic Significance of Cardiac Radionuclide Parameters Obtained in the Early Phase of Acute Myocardial Infarction |
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| Subtitle | Original Articles |
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| Authors | Akio SUZUKI*, Hideo MATSUSHIMA*, Akihiko SATOH*, Hiroshi HAYASHI*, Iwao SOTOBATA**, Toshiya WATANABE***, Hidetaka ITATSU*** |
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| Authors(kana) | |
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| Organization | *The First Department of Internal Medicine, Nagoya University, **The Department of Internal Medicine, Fujita-Gakuen Health University School of Medicine, ***The Department of Internal Medicine, National Nagoya Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 11 |
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| Page | 1607-1616 |
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| Year/Month | 1987/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Seventy-six patients with acute myocardial infarction (AMI) were studied with infarct-avid scan, radionuclide angiography and Tl-201 myocardial perfusion scintigraphy. Infarct area, defect score and left ventricular ejection fraction (LVEF) were calculated as radionuclide indices of the extent of AMI. Each of these indices significantly correlated with maxCK. The correlation was studied between these indices and cardiac events (death, congestive heart failure, postinfarction angina and recurrence of AMI) in the first postinfarction year. High-risk patients (nonsurvivors or patients who developed heart failure) had a larger infarct area, a lower LVEF and a larger defect score than the others. Univariate linear discriminant analysis was performed to know the optimal threshold of these parameters for separation of high-risk patients from the others. Radionuclide parameters obtained in the early phase of AMI were useful for the detection of patients with grave complications and also those with poor late prognosis during a mean follow-up period of 2.6 years. |
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| Practice | Clinical medicine |
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| Keywords | Acute myocardial infarction, Radionuclide parameters, Cardiac events, Late prognosis. |
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