Japanese
Title心筋虚血の検出における運動負荷タリウムSPECTの各種解析法の比較
Subtitle原著
Authors児島陽一*, 村田啓**, 西村重敬***
Authors(kana)
Organization*岩手医科大学放射線科, **虎の門病院放射線科, ***循環器センター内科
Journal核医学
Volume24
Number10
Page1511-1520
Year/Month1987/10
Article原著
Publisher日本核医学会
Abstract「要旨」 労作性狭心症55例と正常対照者10例に, 運動負荷タリウム心筋single photon emission CT (SPECT) を施行し, 視覚判定法, circumferential profile解析 (CP) , washout rate解析 (WR) , Bull's eye表示 (BE) を行い, 各冠動脈支配領域別の虚血領域検出率を比較検討した, 視覚判定法では, 前下行枝 (LAD) 領域, 右冠動脈 (RCA) 領域の虚血領域検出におけるsensitivityが比較的良好であり, specificityも各種解析間で最も優れていた. しかし, 回旋枝 (LCX) 領域におけるsensitivityと多枝病変における虚血領域検出率は, やや低い値であった. CPおよびBEは, 視覚判定法と比較すると, 同等あるいはそれ以下であった. WRのsensitivityは, 各種解析間で最も高く, LCX病変, 多枝病変についても良好な成績であった. また, WRより求めたwashout rate scoreは, 病変の重症度と相関した. したがって, 領域別の虚血の診断および評価には, 視覚判定法とWRの併用が最も有効であると結論された.
Practice臨床医学:一般
KeywordsEffort angina, Myocardial SPECT, Bull's eye display, Washout rate, Circumferential profile analysis
English
TitleComparative Evaluation of Some Analyses of Stress-redistribution Thallium-201 Myocardial SPECT for Myocardial Ischemia
SubtitleOriginal Articles
AuthorsYoichi KOJIMA*, Hajime MURATA**, Shigeyuki NISHIMURA**
Authors(kana)
Organization*Department of Radiology,School of Medicine, Iwate Medical University, **Division of Nuclear Medicine and Cardiovascular Center, Toranomon Hospital
JournalThe Japanese Journal of nuclear medicine
Volume24
Number10
Page1511-1520
Year/Month1987/10
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Stress-redistribution thallium-201 (201Tl) myocardial single photon emission CT was performed in 55 patients with effort angina and 10 normal subjects. Visual interpretation and some quantitative expressions, which were maximum-count circumferential profile for myocardial distribution of 201Tl, segmental washout rate and each Bull's eye display, were analyzed to evaluate detectability for the territories of stenotic coronary arteries. The sensitivity of the visual method for detection of disease in LAD and RCA was fairly good and the specificity in each of the coronary artery was the highest in every analyses. However, the sensitivity for LCX and detectability in patient with multiple vessel disease were low. Accuracies of circumferential profile analysis and two Bull's eye display were equal or low as compared with visual method. Sensitivity of segmental washout rate was the highest value in every analyses and showed good results even in the patient with LCX lesion or multiple vessel disease. Washout rate score, which was calculated as the area between the washout rate profile curve and normal lower limits in the abnormal region, correlated well with severity of % coronary artery lumen diameter reduction. So we conclude that the visual method in combination with washout rate analysis is useful diagnostic method for detecting and evaluating patient with effort angina.
PracticeClinical medicine
KeywordsEffort angina, Myocardial SPECT, Bull's eye display, Washout rate, Circumferential profile analysis

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