| Japanese |
|---|
| Title | 同部位同時シンチグラフィによるIn-111ならびにTc-99m2核種の骨髄内分布の比較 - 骨髄輪郭決定のための画像処理 - |
|---|
| Subtitle | 原著 |
|---|
| Authors | 宇山親雄*, 高橋豊** |
|---|
| Authors(kana) | |
|---|
| Organization | *国立循環器病センター研究所, **天理よろづ相談所病院 |
|---|
| Journal | 核医学 |
|---|
| Volume | 24 |
|---|
| Number | 10 |
|---|
| Page | 1499-1510 |
|---|
| Year/Month | 1987/10 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」 活性骨髄の全身性分布を知る目的で, 造血髄と細網内皮系随との間で親和性に差があるとされるIn-111クロライドとTc-99m-Sコロイドの2核種を投与し, エネルギーレベルの異なる2つのシンチグラムを同時に得た. まず, 本質的に複雑な形状を持つ活性骨髄の輪郭の描出に当たり, 総合分解能に関する像のボケと同位元素崩壊過程の統計的ばらつき由来の雑音との両者の補正を調和させる方法を検討し, 最適フィルタ法が良い結果を与えることを確かめた. つぎに, Tc-99mとIn-111の両活性が混在する低エネルギー域シンチグラムからTc-99mの分布像を分離するため, In-111由来の放射能を除く処理を行い, Tc-99mのみの骨髄内分布像を得た. こうしてIn-111分布像とTc-99m分布像との比較が可能となった. さらに, 両核種活性間の相関係数をより正確に求め, 両者の分布上の相似あるいは解離性を判断する上で, また臨床病態の把握の上で有用性が期待される指標を得た. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Bone marrow scintigram, Image processing, Double tracers |
|---|
| English |
|---|
| Title | Image Processing on the Distribution Patterns of In-111 Chloride and Tc-99m Colloid Recorded Simultaneously from the Bone Marrow |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Chikao UYAMA*, Yutaka TAKAHASHI** |
|---|
| Authors(kana) | |
|---|
| Organization | *Research Institute, National Cardiovascular Center, **RI Center and Hematology Tenri Hospital |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 24 |
|---|
| Number | 10 |
|---|
| Page | 1499-1510 |
|---|
| Year/Month | 1987/10 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] For imaging the functioning bone marrow, which includes both hematopoietic and reticuloendothelial elements, Tc-99m-S colloid and In-111-C1 were administered to subjects to label both marrow elements, and scintigraphy was done at 140 KeV and 247 KeV in the dual channel mode. First we applied two methods of static image processing, 9 point smoothing and optimum filter, and compared the results. The optimum filter was superior to 9 point smoothing for obtaining by isocount tracing a reasonable contour of the functioning marrow. Furthermore, this filter improved resolution while minimizing noise fluctuation. In the second step, the In-111 count obtaining at 247 KeV was subtracted from that at 140 KeV by multiplying the former by a certain factor. Background subtraction was also done by determining the average count in the area outside the functioning marrow. Net Tc-99m and In-111 counts thus obtained were compared for every pixel within the delineated marrow area to yield a correlation coefficient of intramedullary distribution between both tracers as a quantitative indicator of determining similarity or dissimilarity between Tc-99m-S and In-111-C1 bone marrow images. The coefficient values for the two image processing methods differed, but this difference was considered to be insignificant in the clinical use. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Bone marrow scintigram, Image processing, Double tracers |
|---|