Japanese
Title運動負荷心筋シンチグラフィによる左冠動脈主幹部病変の検出精度に関する検討
Subtitle原著
Authors木原浩一*,***, 西村恒彦*, 植原敏勇*, 林田孝平*, 住吉徹哉**, 斉藤宗靖**
Authors(kana)
Organization*国立循環器病センター放射線診療部, **内科, ***現 ; 鹿児島大学医学部第一内科
Journal核医学
Volume24
Number10
Page1473-1481
Year/Month1987/10
Article原著
Publisher日本核医学会
Abstract「要旨」 左冠動脈主幹部 (LMT) 病変は致命率の高い虚血性心疾患であり, 非観血的で精度の高い検出方法の確立が望まれる. そこで著者らは, 心筋梗塞を合併しないLMT病変24例において, 運動負荷心筋シンチグラフィ上の特徴と検出精度について検討した. 特徴的な所見とされるLMT patternは29% (7例/24例) に見られた. LMTの狭窄度が90%以上 (12例) と未満の群 (12例) では, その出現率はそれぞれ58% (7例/12例) , 0% (0例/12例) であった. また, 右冠動脈病変の有無で分けると, それぞれ21% (3例/14例) , 40% (4例/10例) であった. LMT patternの出現は, LMTの狭窄度および右冠動脈病変の有無に左右されることが示唆された. 運動負荷心筋シンチグラフィにおいて, LMT pattern, diffuse slow washout, Tl-lung uptakeの増加に加え, 2mm以上のST低下, 低負荷時よりの有意なST低下, 10mmHg以上の収縮期血圧の低下から総合的に判定することでLMT病変の検出精度が83%に向上した.
Practice臨床医学:一般
KeywordsLeft main coronary artery disease, Exercise thallium-201 myocardial scintigraphy, Exercise electrocardiography
English
TitleExercise Thallium-201 Myocardial Scintigraphy in Left Main Coronary Artery Disease : Assessment of High Risk Scintigraphic and Electrocardiographic Findings
SubtitleOriginal Articles
AuthorsKoichi KIHARA, Tsunehiko NISHIMURA, Toshiisa UEHARA, Kohei HAYASHIDA, Tetsuya SUMIYOSHI, Muneyasu SAITO
Authors(kana)
OrganizationDepartment of Radiology and Cardiology, National Cardiovascular Center
JournalThe Japanese Journal of nuclear medicine
Volume24
Number10
Page1473-1481
Year/Month1987/10
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] To detect left main (LM) coronary artery disease (CAD) , exercise thallium-201 myocardial scintigraphy was analyzed in 24 patients (LM stenosis>50%) without myocardial infarction and 10 normal controls. A high risk myocardial scintigraphy was defined as follows ; (1) a LMCAD scintigraphic pattern reported by Dash, (2) nonuniform diffuse slow washout, (3) increased lung thallium uptake on the initial anterior image. Twenty-three (96%) patients had an abnormal scintigraphic findings. The LMCAD scintigraphic pattern was found in seven (29%) patients, all of whom had LM stenosis more than 90%. Remaining 17 patients with LM stenosis less than 90% didn't show this pattern. In the 10 LMCAD patients without right coronary artery (RCA) lesion, four (40%) patients showed this pattern. But in the 14 LMCAD patients with RCA lesion, three (21%) patients showed this pattern. In this study, a high risk exercise electrocardiography was also defined as follows ; (1)>2 mm ST depression, (2) appearance of ST depression at 50 watt or less exercise load, (3) 10 mmHg or more decrease in systolic blood pressure during exercise. Detection of high risk CAD with exercise electrocardiography, exercise thallium scintigraphy and either were 46, 67, 83%, respectively.
PracticeClinical medicine
KeywordsLeft main coronary artery disease, Exercise thallium-201 myocardial scintigraphy, Exercise electrocardiography

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