| Japanese |
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| Title | Tc-99m-標識赤血球を用いた定量的下肢血流量測定 - Radionuclide venous occlusion plethysmography (RAVOP) について - |
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| Subtitle | 原著 |
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| Authors | 伊藤和夫*, 勝賀瀬貴**, 川村直之*, 塚本江利子*, 中駄邦博*, 佐久間まこと***, 古舘正従* |
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| Authors(kana) | |
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| Organization | *北海道大学医学部核医学講座, **循環器内科学講座, ***第二外科学講座 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 10 |
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| Page | 1465-1472 |
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| Year/Month | 1987/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 組織内非拡散性放射性薬剤である Tc-99m-標識赤血球 (RBC) を用いた下肢血流の定量的解析法に関して検討した. 解析はFukuokaらが報告したradionuclide venous occlusion Plethysmography (RAVOP) の結果を応用した. 本検査法で得られた正常群 (30肢) と動脈閉塞肢 (12肢) および心疾患群 (46肢) の下肢血流量 (平均±標準誤差) はそれぞれ1.87±0.08ml/100ml/minと1.49±0.13ml/100ml/minおよび1.35±0.08ml/100ml/minで正常群と疾患両群との間にはそれぞれ有意差 (p<0.01) が認められた. 検査は従来のTc-99m-RBCを用いた検査に引続いて施行でき, 定量的な解析のための算出式もきわめて簡単である. 非侵襲的な新しい定量的下肢血流量の評価法であることが確認された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Blood flow, Tc-99m labeled red blood cells, Plethysmography, Occlusive arterial disease, Heart disease |
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| English |
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| Title | Quantitative Assessment of Limb Blood Flow Using Tc-99m Labeled Red Blood Cells : Radionuclide Venous Occlusion Plethysmography (RAVOP) |
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| Subtitle | Original Articles |
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| Authors | Kazuo ITOH*, Takashi SHOUGASE**, Naoyuki KAWAMURA*, Eriko TSUKAMOTO*, Kunihiro NAKADA*, Makoto SAKUMA***, Masayori FURUDATE* |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine, **Department Of Cardiovascular Internal Medicine, ***Second Department of Surgery, School of Medicine, Hokkaido University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 10 |
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| Page | 1465-1472 |
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| Year/Month | 1987/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A quantitative assessment of limb blood flow using a non-diffusible radioindicator, Tc-99m labeled red blood cells, was reported. This was an application of venous occlusion plethysmography using radionuclide which was originally proposed by M.Fukuoka et al. The peripheral blood flow (mean+-s.e.) of 30 legs in a normal control group was 1.87+-0.08 ml/100 ml/min. In heart diseases (46 legs) , it was 1.49+-0.13 ml/100 ml/min. The limb blood flow between a control group and heart diseases was statistically significant (p<0.01) in the t-test. The peripheral blood flow at rest between diseased legs and normal legs in occlusive arterial disorders was also statistically significant (p<0.01) in a paired t-test. RAVOP was done after the completion of objective studies such as radionuclide angiography or ventriculography. Technique and calculation of a blood flow were very easy and simple. RAVOP study which was originally proposed by Fukuoka et al. was reappraised to be hopeful for quantitative measurement of limb blood flow as a noninvasive technique using Tc-99m labeled red blood cells. |
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| Practice | Clinical medicine |
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| Keywords | Blood flow, Tc-99m labeled red blood cells, Plethysmography, Occlusive arterial disease, Heart disease |
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