| Japanese |
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| Title | 肥大型心筋症におけるタリウム心筋灌流異常に関する検討 - 心エコー図, 血行動態, および血中心筋逸脱酵素所見との対比を中心として - |
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| Subtitle | 原著 |
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| Authors | 西村恒彦*, 永田正毅**, 植原敏勇*, 林田孝平*, 小塚隆弘*, 榊原博** |
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| Authors(kana) | |
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| Organization | *国立循環器病センター放射線診療部, **内科 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 9 |
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| Page | 1365-1376 |
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| Year/Month | 1987/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」肥大型心筋症114例に安静時心筋シンチグラフィ, 32例に負荷心筋シンチグラフィを施行, 本症における心筋灌流異常の出現について, 心エコー図, 心血行動態, 血中心筋逸脱酵素所見などと対比検討した. 安静時心筋シンチグラフィにて(A)群:欠損像のない85例(75%)と(B)群:欠損像を有する29例(25%)に大別できた. 後者は, (1)家族性で, 欠損像を有し血中心筋逸脱酵素の上昇した10例(5家系), (2)家族性ははっきりしないが(1)と同様に心拡大, 心機能の低下を有する10例, および(3)欠損は有するが心拡大・心機能低下のない9例に分類された. また, (A)群では負荷心筋シンチグラフィにて32例中17例(53%)に一過性欠損像を有した. その出現部位は心筋肥大部位を中心として出現したが安静時心機能は正常であった. また, これらの症例はすべて正常冠動脈所見を有した. この欠損像の成因の一つとして, small coronary artery diseaseの関与が示唆された. 心筋シンチグラフィは肥大型心筋症のうち, (B)群のように心筋肥大とともに心筋線維化を有する症例を早期に検出する上で非常に有用なことが示された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Hypertrophic cardiomyopathy, Thallium myocardial imaging, Perfusion defect. |
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| English |
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| Title | Abnormal Thallium Myocardial Perfusion in Hypertrophic Cardiomyopathy : Comparison with Echocardiographic, Hemodynamic, and Serum Enzyme Findings |
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| Subtitle | Original Articles |
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| Authors | Tsunehiko NISHIMURA, Seiki NAGATA, Toshiisa UEHARA, Kohei HAYASHIDA, Takahiro KOZUKA, Hiroshi SAKAKIBARA |
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| Authors(kana) | |
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| Organization | Department of Radiology and Department of Cardiology, National Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 9 |
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| Page | 1365-1376 |
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| Year/Month | 1987/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]Thallium scan was performed in 114 cases of hypertrophic cardiomyopathy (HCM). Then, HCM was divided into (A) 85 typical and (B) 29 atypical cases. The latter had persistent defect (PD) in apical or septal wall. There were (1) 10 cases of familial HCM, (2) 9 cases of dilated left ventricle and (3) 10 cases without dilated left ventricle. Group B-1 had large LVEDVI (134+-54 ml/m2), lower LVEF (32+-13%), elevation of CPK, LDH and abnormal, histological findings. These data suggest, PD as scar formation. Group B-2 had also large LVEDVI (94+-18 ml/m2) and lower LVEF (42+-8%). However, group B-3 showed normal LVEDVI and LVEF. Stress thallium scan was also performed in 32 cases of typical HCM (group A). Seventeen (57%) of all had transient defect in spite of normal coronary artery. These findings may be caused by relative ischemia due to myocardial hypertrophy, narrowing of intramural coronary artery or small coronary artery disease. Although extension of myocardial hypertrophy was not known, these observation from thallium scan was very useful for the assessment of myocardial fibrosis of HCM. |
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| Practice | Clinical medicine |
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| Keywords | Hypertrophic cardiomyopathy, Thallium myocardial imaging, Perfusion defect. |
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