| Japanese |
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| Title | 局所冠血流および乳酸代謝からみた梗塞巣におけるTl-201再分布現象の意義 |
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| Subtitle | 原著 |
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| Authors | 森孝夫*, 山辺裕*, 須田研一郎*, 大西正孝*, 塩谷英之*, 栗本泰行*, 小林克也*, 前田和美**, 福崎恒* |
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| Organization | *神戸大学医学部第一内科, **神戸大学医療技術短期大学部 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 9 |
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| Page | 1321-1327 |
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| Year/Month | 1987/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」梗塞領域におけるTl-201心筋シンチグラフィー上のredistribution(RD)現象の臨床的意義を明らかにするため, 陳旧性心筋梗塞症13例において梗塞巣14領域への冠血流を直接測定し, dipyridamole負荷時の反応性とRD現象との関係を検討した. RD現象陽性11領域の冠血流増加率はRD現象陰性3領域に比し低く, また乳酸摂取率も低い傾向を示した. RD現象陽性のうち負荷時乳酸産生に至った領域は前者の5領域にすぎなかった. 乳酸産生に至った5領域と至らなかった6領域を比べると, 左室拡張末期圧の上昇は乳酸産生陽性例でのみ認められ, 乳酸産生陰性例と異なった反応を示したが, 冠血流増加率およびTl-201 image上のRD現象には差異を認めなかった. 以上より梗塞領域に認められたRD現象は同部位に生じた一過性虚血とともに虚血を惹きおこすに至らない冠血流増加反応の低下をも表現すると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium-201 redistribution, Dipyridamole, Coronary sinus flow. |
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| English |
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| Title | Significance of Tl-201 Redistribution on Infarcted Region Assessed by Coronary Sinus Flow and Lactate Metabolism |
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| Subtitle | Original Articles |
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| Authors | Takao MORI, Hiroshi YAMABE, Kenichirou SUDA, Masataka OHNISHI, Hideyuki SHIOTANI, Yasuyuki KURIMOTO, Katsuya KOBAYASHI, Kazumi MAEDA, Hisashi FUKUZAKI |
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| Organization | The First Department of Internal Medicine, Kobe Universiry School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 9 |
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| Page | 1321-1327 |
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| Year/Month | 1987/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]To clarify the significance of Tl-201 redistribution on infarcted regions, coronary sinus and great cardiac vein flow response and lactate metabolism assessed by Webster catheter on 14 infarcted regions after dipyridamole administration were compared with Tl-201 redistribution phenomenon. The regional coronary flow response and lactate extraction ratio in 11 regions with Tl-201 redistribution were lower than those in 3 regions without Tl-201 redistribution. Only 5 regions in 11 with Tl-201 redistribution showed lactate production. The coronary flow response in 5 regions with lactate production was not different from those in 6 without lactate production (1.16+-0.89 vs. 1.47+-0.67; n. s.). The degree of Tl-201 redistribution assessed by relative activity was not different between regions with and without lactate production. The left ventricular end-diastolic pressure elevated in 5 regions with lactate production (17.8+-5.4 mmHg to 29.6+-4.9 mmHg; p<0.05), but didn't in 6 regions without lactate production. Five regions with lactate production contained 4 hypokinetic regions, on the other hand 6 regions without lactate production contained only 3 hypokinetic regions. In conclusion, Tl-201 redistribution on infarcted region revealed not only ischemia but also decreased coronary flow response without lactate production and/or left ventricular dysfunction. |
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| Practice | Clinical medicine |
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| Keywords | Thallium-201 redistribution, Dipyridamole, Coronary sinus flow. |
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