| Japanese |
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| Title | 間質性肺疾患における67Gaシンチグラフィの評価 - 核医学データ処理装置を用いた解析 - |
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| Subtitle | 原著 |
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| Authors | 藤田明*, 酒井良介**, 金子昇*, 斎藤学*, 長尾啓一*, 渡辺昌平*, 栗山喬之*, 国安芳夫*** |
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| Authors(kana) | |
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| Organization | *千葉大学医学部肺癌研究施設内科, **社会保険船橋中央病院放射線部, ***帝京大学医学部放射線医学 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 9 |
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| Page | 1313-1320 |
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| Year/Month | 1987/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」正常例および間質性肺疾患症例を対象に, 肺における67Ga citrateの集積についてガンマカメラに接続した核医学データ処理装置を用いて解析した. 全身総カウントに対する肝臓の67Ga摂取率は, 症例間でばらつきが少なく, 肺野および肺門の67Ga集積を計測視野内の肝右葉を基準として評価した. 左右上下4肺野領域, 肝右葉に関心領域(ROI)の設定を行い, それぞれのROIについて1pixel当たりの平均カウントを求め, 肺野4領域について肝右葉を100として摂取率を算定した. 4領域の平均値(67Ga computer index)は正常例(n=5)37.8±2.5, サルコイドージスI期例(n=12)44.0±4.9, II期例+III期例(n=6)54.7±11.3, 肺線維症症例(n=6)49.3±3.5, 塵肺症症例(n=7)67.3±24.6で, いずれも正常例に比して有意に高値を示した. 胸部X線上肺野病変を認めないサルコイドージスI期例でも正常肺に比して高値(p<0.01)であった. 肺野部位別の67Ga集積の検討では, サルコイドージスI期例, 肺線維症症例で胸部X線所見と合致しない例のあることが明らかにされた. 67Gaシンチグラフィのデータ処理装置を用いた解析によって, 胸部X線上あらわれにくい間質性肺疾患の病変を容易に検出できる可能性が示唆された. |
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| Practice | 臨床医学：一般 |
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| Keywords | 67Ga scintigraphy, Interstitial pulmonary disease, Sarcoidosis, Pulmonary fibrosis. |
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| English |
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| Title | Computed Analysis of Ga-67 Scintigraphy in Patients with Interstitial Pulmonary Diseases |
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| Subtitle | Original Articles |
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| Authors | Akira FUJITA*, Ryosuke SAKAI**, Noboru KANEKO*, Manabu SAITOH*, Keiichi NAGAO*, Shohei WATANABE*, Takayuki KURIYAMA*, Yoshio KUNIYASU*** |
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| Authors(kana) | |
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| Organization | *Department of Chest Medicine, Institute of Pulmonary Cancer Research, School of Medicine, Chiba University, **Department of Radiology, Funabashi-chuoh Hospital, ***Department of Radiology, School of Medicine, Teikyo University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 9 |
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| Page | 1313-1320 |
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| Year/Month | 1987/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]We assessed Ga-67 uptake in lung in normal subjects and patients with interstitial pulmonary diseases, using a computer linked to a gamma camera. There was a small variation in the ratios of Ga-67 counts in liver to total body counts. As the standard in the field of view, the right lobe of the liver was used to assess Ga-67 uptake in lung. The regions of interest corresponding to the right upper lung field, the right lower lung field, the left upper lung field, the left lower lung field and the right lobe of the liver were delineated. The average counts/pixel were determinated. Ga-67uptake value in each lung field was calculated as percentage of the average counts in the right lobe of the liver. The average percentage of 4 lung fields (presented as Ga-67 computer index) was 37.8+-2.5 in normal subjects (n=5), 44.0+-4.9 in stage I (bilateral hilar lymphadenopathy without lung involvement on chest X-ray) sarcoidosis (n=12), 54.7+-11.3 in stage II・III (lung involvement) sarcoidosis (n=6), 49.3+-3.5 in pulmonary fibrosis (n=6) and 67.3+-24.6 in pneumoconiosis (n=7. Particularly Ga-67 computer index in patients with stage I sarcoidosis was significantly higher than in normal subjects (p<0.01). Our study clarified that the differences of regional Ga-67uptake values were not parallel to the views on the chest X-ray especially in the cases with stage I sarcoidosis and pulmonary fibrosis. These results suggested that computed analysis of Ga-67 scintigraphy might detect abnormalities which were not recognized on chest X-ray in interstitial pulmonary diseases. |
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| Practice | Clinical medicine |
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| Keywords | 67Ga scintigraphy, Interstitial pulmonary disease, Sarcoidosis, Pulmonary fibrosis. |
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