| Japanese |
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| Title | タリウム2回投与法による非観血的冠予備能測定法の検討 |
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| Subtitle | 原著 |
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| Authors | 津田隆志*, 閏間美智子*, 古寺邦夫*, 山本朋彦*, 柴田昭*, 木村元政**, 小田野幾雄**, 浜斎***, 三谷亨*** |
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| Organization | *新潟大学医学部第一内科, **放射線科, ***木戸病院RI室 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 7 |
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| Page | 927-931 |
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| Year/Month | 1987/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」局所冠血流量を反映する201Tl心筋摂取カウントを用いて, 非観血的冠血流予備能(CFRn)を求め, 観血法(CFRi)との比較, 各種疾患での検討を行った. CFRnは, 安静時とDipyridamole静注後の最大冠血管拡張時の心筋カウントの比より求めた. CFRiは, 熱希釈法による冠血流量の比を用いて求めた. Control(C)6例, CAD9例, 高血圧心(HHD)6例, HCM13例の合計34例で検討し, 9例でCFRiも測定した. CFRnはCFRiと有意な正相関(r=0.81, p<0.01)を認めた. CFRnは, C:3.70±0.74に比し, CADの非梗塞部:2.22±0.19・梗塞部:2.29±0.17, HHD:2.35±0.27, HCM:2.42±0.23といずれも有意な低値を示した(p<0.001〜0.005). また, CADの非梗塞部位では, 冠動脈狭窄の進行につれて, CFRnは有意に低下した. 本法は, 観血法とも良い正相関を示し, HHD, HCMで低値を示し, CADでは罹患病変部位別・重症度別の冠予備能測定も可能であった. 本法は, 簡便な冠予備能測定法として有用と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Coronary reserve, Thallium-201, Coronary artery disease, Hypertensive heart disease, Hypertrophic cardiomyopathy. |
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| English |
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| Title | Assessment of Noninvasive Coronary Flow Reserve by Two-Successive Imaging Method Using Thallium-201 |
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| Subtitle | Original Articles |
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| Authors | Takashi TSUDA*, Michiko URUMA*, Kunio KODERA*, Tomohiko YAMAMOTO*, Akira SHIBATA*, Motomasa KIMURA**, Ikuo ODANO**, Hitoshi HAMA***, Tohru MITANI*** |
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| Authors(kana) | |
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| Organization | *The First Department of Internal Medicine, **Department of Radiology, Niigata University School of Medicine, ***Kido Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 7 |
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| Page | 927-931 |
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| Year/Month | 1987/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]Noninvasive coronary flow reserve (CFRn) was examined by two-successive imaging method using thallium-201 and compared with invasive method (CFRi). CFRn was calculated using Tl myocardial uptake counts before and after dipyridamole loading (0.568 mg/kg/4 min). CFRi was calculated using coronary blood flow by thermodilution method. Patients studied were 9 with coronary artery disease (CAD), 6 with hypertensive heart disease (HHD), 13 with hypertrophic cardiomyopathy (HCM) and 6 control. Among them, CFRi was examined in 9 patients. There were significant positive correlation between CFRn and CFRi (r=0.81, p<0.01). CFRn was 2.22+-0.19 in noninfarcted area with CAD, 2.29+-0.17 in infarcted area with CAD, 2.35+-0.27 in HHD and 2.42+-0.23 in HCM, respectively. They were significantly lower than that (3.70+-0.74) in control (p<0.001〜0.005). In noninfarcted area with CAD, CFRn (2.06+-0.74) in severe stenotic area was significantly lower than that (2.33+-0.10) in moderate Stenotic area. In conclusion, CFRn was the effective method in assessment of coronary reserve noninvasively. |
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| Practice | Clinical medicine |
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| Keywords | Coronary reserve, Thallium-201, Coronary artery disease, Hypertensive heart disease, Hypertrophic cardiomyopathy. |
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