| Japanese |
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| Title | Tl-201心筋SPECTの新しい定量的表示法 (展開図法) に関する基礎的検討 |
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| Subtitle | 原著 |
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| Authors | 島田智好*, 栗本透*, 神畠宏*, 唐川正洋*, 松浦隆*, 小椋英司*, 羽田哲也*, 浜口保武*, 稲田満夫*, 西山豊**, 白石友邦** |
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| Organization | *関西医科大学第二内科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 6 |
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| Page | 853-863 |
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| Year/Month | 1987/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」Tl-201心筋SPECTによる診断能の向上と虚血の定量化を目的として展開図法を考案作製し, その実用性に関する基礎的検討を行った. SPECT短軸像のprofile dataをその外接円周に基づき展開し配列表示した. 欠損領域は一定の基準値(%MC)により判定しその領域面積は全展開図面積に対する比例計算で算出した. Phantomを用いた検討では直径20, 30mm欠損の実測面積に対する本法の測定誤差は平均26%であった. また心筋梗塞, 狭心症, 健常例各5例に対して運動負荷SPECTを施行, 再分布時に欠損を検出し得ない最大基準値にそれぞれ約10%MCの差を認め, 虚血, 梗塞領域の判定には異なった2種の基準値が必要と考えられた. 虚血性心疾患31例における虚血, 梗塞に関する本法のaccuracyはそれぞれ84%, 82%であった. また本法で計測した梗塞面積と壁運動異常の程度, 駆出率とは有意に相関した. 以上より, 本法は心筋虚血の診断, 定量に関して十分臨床応用可能と考えられる. |
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| Practice | 臨床医学：一般 |
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| Keywords | Tl-201 myocardial SPECT, Coronary artery disease, Quantitative analyzing, The unfolded map, Two-dimensional representation. |
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| English |
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| Title | The Unfolded Map : Quantification of Tl-201 Myocardial Single Photon Emission Computed Tomography |
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| Subtitle | Original Articles |
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| Authors | Tomoyoshi SHIMADA*, Tohru KURIMOTO*, Hiroshi KAMIHATA*, Masahiro KARAKAWA*, Takashi MATSUURA*, Eiji OGURA*, Tetsuya HATA*, Yasutake HAMAGUCHI*, Mitsuo INADA*, Yutaka NISHIYAMA**, Tomokuni SHIRAISHI** |
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| Authors(kana) | |
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| Organization | *The Second Department of Internal Medicine, **The Department of Radiology, Kansai Medical University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 6 |
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| Page | 853-863 |
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| Year/Month | 1987/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]A new method was devised using Tl-201 myocardial SPECT to quantify the extent of myocardial ischemia and to improve the diagnostic usefulness, and a basic study for the clinical application of this method was performed. After the perimeters of short axis tomograms were determined using cut-off value, maximal count profiles of each tomograms were unfolded and were arranged in order from apex to base of left ventricle into two-dimensional plane. The abnormal defect was defined as the region below the standard value (percent max. count, %MC) and the area of this region was calculated as ratio of hypoperfusional to total pixels of whole map area. In the study using the left ventricular phantom, the relative error of calculated defect area were 26.4+-23.5 (mean+-SD). In 15 patients (myocardial infarction (MI): 5, angina pectoris (AP): 5, no coronary artery disease (Cont.): 5), the unfolded maps were obtained immediately and 4 hours (RD) after exercise stress. The maximal standard value that the perfusion defect could not be detected in RD map were as follows, MI; 47.9+-10.3, AP; 56.4+-4.5, Cont.; 66.0+-1.7%MC. Therefore, two standard values are necessary for detecting the transient ischemic and the infarcted region. In 31 patients with coronary artery disease, accuracy of this method using two standard values were 84% and 82%, in AP and MI, respectively. And there were significant correlations between the infarcted area obtained by this method and the asynergy score of LVG and the ejection fraction. This method is useful for the diagnosis and the quantification of myocardial ischemia. |
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| Practice | Clinical medicine |
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| Keywords | Tl-201 myocardial SPECT, Coronary artery disease, Quantitative analyzing, The unfolded map, Two-dimensional representation. |
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