| Japanese |
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| Title | 慢性肝内胆汁うっ滞の肝胆道シンチグラフィ - 原発性硬化性胆管炎の診断を主体に - |
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| Subtitle | 《原著》 |
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| Authors | 油野民雄*, 高山輝彦*, 秀毛範至*, 絹谷清剛*, 利波紀久*, 久田欣一*, 平井信行**, 田中延善**, 小林健一**, 服部信** |
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| Authors(kana) | |
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| Organization | *金沢大学医学部核医学教室, **第一内科学教室 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 5 |
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| Page | 543-550 |
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| Year/Month | 1987/5 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」原発性胆汁性肝硬変(PBC)11例および原発性硬化性胆管炎(PSC)3例の慢性肝内胆汁うっ滞計14例を対象として, 肝胆道シンチグラフィによる両疾患鑑別の可能性に関し検討した. 肝内胆管と肝外胆管が障害されたタイプ1例および肝内胆管のみに障害がみられたタイプ2例のPSC 3例全例では, ERCPでみられた肝内胆管の硬化性変化に一致して肝内にRI停滞像が認められたのに対し, 逆にPBC 11例全例では肝内にRI停滞像は認められなかった. 以上より肝胆道シンチグラフィは, 慢性肝内胆汁うっ滞患者の評価, 特にPBCとPSCとの鑑別の目的で, PTCやERCP等直接胆道造影施行前の非侵襲的一次検査法として有効と思われた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Hepatobiliary scintigraphy, Chronic intrahepatic cholestasis, Primary sclerosing cholangitis, Primary biliary cirrhosis. |
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| English |
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| Title | Hepatobiliary Scintigraphy in Chronic Intrahepatic Cholestasis - Diagnosis of Primary Sclerosing Cholangitis - |
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| Subtitle | Original Article |
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| Authors | Tamio ABURANO*, Teruhiko TAKAYAMA*, Noriyuki SHUKE*, Seigo KINUYA*, Norihisa TONAMI*, Kinichi HISADA*, Nobuyuki HIRAI**, Enzen TANAKA**, Kenichi KOBAYASHI**, Nobu HATTORI** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine, **First Department of Internal Medicine, Kanazawa University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 5 |
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| Page | 543-550 |
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| Year/Month | 1987/5 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | Primary sclerosing cholangitis (PSC) is a rare disease of unknown origin, leading to chronic intermittent cholestasis. Due to its low incidence, insidious clinical onset and varied clinical picture, the diagnosis is often delayed by years. PSC is sometimes diagnosed falsely as another disease of chronic intermittent cholestasis, primary biliary cirrhosis (PBC). In the present study, the hepatobiliary imaging with Tc-99m diethyl IDA was done in a total of 14 patients with chronic intermittent cholestasis including 3 patients with PSC and 11 patients with PBC, in order to decide its clinical usefulness as a noninvasive method for the differentiation between PSC and PBC. All three patients with PSC showed a typical pattern of radionuclide stasis within the area of intrahepatic and/or extrahepatic ductal system, representing the stenosis on endoscopic retrograde cholangiogram. On the other hand, none of 11 patients with PBC showed any radionuclide stasis within the area of intrahepatic and/or extrahepatic ductal system. This result suggests that the radionuclide hepatobiliary imaging may be a noninvasive method for investigating patients with chronic intermittent cholestasis, leading to earlier differentiation between PSC and PBC. |
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| Practice | Clinical medicine |
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| Keywords | Hepatobiliary scintigraphy, Chronic intrahepatic cholestasis, Primary sclerosing cholangitis, Primary biliary cirrhosis. |
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