| Japanese |
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| Title | 超短半減期核種81mKrによる右心機能負荷試験への応用 - ガンマカメラを用いて - |
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| Subtitle | 《原著》 |
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| Authors | 河村康明* |
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| Authors(kana) | |
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| Organization | *東邦大学医学部付属大森病院第一内科 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 5 |
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| Page | 535-541 |
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| Year/Month | 1987/5 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」81Rb-81mKrジェネレータを用いて, 81mKrの右心機能への応用を1)安静時における再現性, 99mTc-HSA・99mTc-MAA first passのright ventricular ejection fraction(RVEF)と比較, 2)運動・薬剤併用intervention study(isosorbide dinitrate 9例, nifedipine 9例)を施行し, その有用性を確認した. 81mKrの持続注入法での再現性はy=0.92x+2.7(r=0.97, p<0.01, n=9), 99mTc-HSA・99mTc-MAAとのRVEFの相関はそれぞれ, y=0.97x-0.48(r=0.86, p<0.01, n=23), y=1.0x-1.8(r=0.96, p<0.01, n=9)であった. また運動・薬剤併用試験ではisosorbide dinitrate症例で有意なRVEFの軽減(p<0.05)を認めた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 81mKr, Ultrashort-lived radionuclide, Right ventricular ejection fraction. |
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| English |
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| Title | Evaluation of Right Ventricular Stress Test by Ultrashort-Lived 81mKr -Using γ-camera - |
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| Subtitle | Original Article |
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| Authors | Yasuaki KAWAMURA |
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| Organization | The First Department of Internal Medicine, Toho University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 5 |
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| Page | 535-541 |
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| Year/Month | 1987/5 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | To assess the availability of 81mKr using 81Rb-81mKr generator, I studied (1) reproducibility of 81mKr-RVEF measurement, and compared 81mKr-RVEF with 99mTc-HSA- and 99mTc-MAA-RVEF first pass study, (2) intervention study-exercise stress combined with drug administration (isosorbide dinitrate, 9 cases; nifedipine, 9 cases). Reproducibility of 81mKr-RVEF measurement by continuous elution method was y=0.92x+2.7 (r=0.97, p<0.01, n=9), and correlation with RVEF of 99mTc-HSA and 99mTc-MAA were y=0.97x-0.4 (y=0.97, p<0.01, n=9), y=1.0x-1.8 (r=0.86, p<0.01, n=9) respectively. Furthermore, ΔRVEF during bicycle exercise was increased significantly (p<0.05) at 50 watts between pre- and post-isosorbide dinitrate administration. |
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| Practice | Clinical medicine |
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| Keywords | 81mKr, Ultrashort-lived radionuclide, Right ventricular ejection fraction. |
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